drugset / Trial / NCT00572468
Statin Therapy Versus Placebo Prior to Prostatectomy
Completed
42 enrolled
VA Office of Research and Development
Oregon Health and Science University · collab
RandomizedParallel-groupDouble-blindScreening
Summary
This is a randomized trial comparing the effect of oral simvastatin versus placebo on targets of the mevalonate pathway in men undergoing a prostatectomy as planned management for prostate cancer. Observed tissue effects will be correlated with changes in serum cholesterol and low-density lipoprotein.
Timeline
- Start
- 2007-12
- Primary completion
- 2013-04
- Completion
- 2017-04-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Simvastatin | Small molecule | 40 mg | Oral |