drugset / Trial / NCT00572468

Statin Therapy Versus Placebo Prior to Prostatectomy

NCT00572468

RandomizedParallel-groupDouble-blindScreening

Summary

This is a randomized trial comparing the effect of oral simvastatin versus placebo on targets of the mevalonate pathway in men undergoing a prostatectomy as planned management for prostate cancer. Observed tissue effects will be correlated with changes in serum cholesterol and low-density lipoprotein.

Timeline

Start
2007-12
Primary completion
2013-04
Completion
2017-04-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Simvastatin Small molecule 40 mg Oral

Indications