drugset / Trial / NCT00578760

Does Aspirin Have a Protective Role Against Chemotherapeutically Induced Ototoxicity?

NCT00578760

Unknown 110 enrolled University Health Network, Toronto
RandomizedParallel-groupQuadruple-blindPrevention

Summary

Aspirin (ASA) has been shown, in an animal model, to attenuate the ototoxic properties of cisplatin. The researchers plan to investigate this in patients undergoing cisplatin chemotherapy. The researchers hypothesise that low-dose aspirin can prevent cisplatin induced ototoxicity in the clinical setting.

Timeline

Start
2008-02
Primary completion
Completion
2010-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Aspirin Small molecule 325 mg