drugset / Trial / NCT00579280

Quetiapine SR and Divalproex Sodium ER in the Treatment of Anxiety in Bipolar Disorder With Panic Disorder and/or GAD

NCT00579280

Phase 4 Completed 224 enrolled University of South Florida AstraZeneca · collab
RandomizedParallel-groupDouble-blindTreatment

Summary

The specific aim of this study is to evaluate the efficacy, tolerability, and safety of quetiapine SR monotherapy and divalproex sodium ER monotherapy in comparison to placebo in the treatment of ambulatory bipolar disorder with co-morbid lifetime panic disorder or generalized anxiety disorder and current at least moderately severe anxiety.

Timeline

Start
2007-07
Primary completion
2010-12
Completion
2010-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Divalproex Sodium Small molecule 500 mg
Comparator Divalproex Sodium Small molecule 3000 mg
Comparator Quetiapine Small molecule 50 mg
Comparator Quetiapine Small molecule 300 mg