Albuterol Versus Xopenex in Treatment of Acute Asthma in the Emergency Department (ED)

Summary

The purpose of this study is to determine in a large, double-blind, randomized, prospective pediatric clinical trial whether the use of continuous levalbuterol (Xopenex) in addition to standard emergency department treatment for acute asthma exacerbations will improve the Forced Expiratory Volume in 1 sec (FEV 1) compared to the use of continuous racemic albuterol. The secondary objective is to correlate clinical (hospitalization rates and clinical asthma scores) with plasma levels of (S)-albuterol.

Timeline

Start

2005-09

Primary completion

2009-03

Completion

2009-03

Drugs

Indications