Drugs / Levalbuterol

Regulatory milestones approvals, filings & regulatory actions · 4 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Label expansion US (FDA) XOPENEX HFA 2015-03-12 fda.gov
Label expansions (2) US (FDA) XOPENEX 2002-01-30 – 2015-01-22 fda.gov
Approved US (FDA) XOPENEX 1999-03-25 fda.gov

Trials 26 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 27 trials
Phase 2 NCT00583947 Jan → Dec 2008 asthma Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 2 NCT00625521 Nov 2006 → Jul 2007 discoid lupus erythematosus Astion Pharma A/S Completed No outcome recorded
Phase 2 NCT00685022 Jun → Aug 2003 asthma Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 2 NCT00684866 Jan → Jul 2003 asthma Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 2 NCT00685347 Jan → Jun 2003 exercise-induced bronchoconstriction Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 2 NCT01656811 Oct 2001 → Jul 2002 asthma Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 2 NCT00625157 discoid lupus erythematosus Astion Pharma A/S Completed No outcome recorded
Phase 311 trials
Phase 3 NCT05890638 Aug 2023 → Feb 2024 chronic obstructive pulmonary disease Neutec Ar-Ge San ve Tic A.Ş Unknown No outcome recorded
Phase 3 NCT04446637 Sep 2021 → Sep 2022 chronic obstructive pulmonary disease Neutec Ar-Ge San ve Tic A.Ş Withdrawn No outcome recorded
Phase 3 NCT00809757 Dec 2008 → Jun 2013 asthma Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 3 NCT00268723 Dec 2005 → Feb 2006 exercise-induced bronchoconstriction Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 3 NCT00064389 Jan 2003 → Jul 2005 asthma Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 3 NCT00073814 Dec 2002 → Jun 2003 asthma Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 3 NCT00685425 Oct 2002 → Mar 2003 exercise-induced bronchoconstriction Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 3 NCT00073827 May 2002 → Jan 2003 asthma Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 3 NCT00665600 Feb 2002 → Mar 2003 chronic obstructive pulmonary disease Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 3 NCT00685126 Feb 2001 → Jul 2002 reactive airway disease Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 47 trials
Phase 4 NCT05173584 Nov → Dec 2021 University of Aleppo Unknown No outcome recorded
Phase 4 NCT00831376 Jan 2009 → Apr 2012 asthma University of Dundee Completed No outcome recorded
Phase 4 NCT00830882 Jan 2009 → Jan 2010 asthma University of Dundee Withdrawn No outcome recorded
Phase 4 NCT00585039 Sep 2005 → Mar 2009 asthma Phoenix Children's Hospital Completed No outcome recorded
Phase 4 NCT00325767 May 2004 → Sep 2005 mucus inspissation of respiratory tract Johns Hopkins University Completed No outcome recorded
Phase 4 NCT00124176 Apr 2004 → Feb 2006 status asthmaticus Children's Hospital of Philadelphia Completed No outcome recorded
Phase 4 NCT00667797 Mar 2003 → May 2005 asthma, chronic obstructive pulmonary disease Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase not applicable1 trial
NCT02802111 Jun 2015 → Sep 2017 Children's Hospital Los Angeles Completed No outcome recorded
Also used as a comparator or background therapy in 14 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT05366764 Background Jun 2022 → Feb 2023 asthma Sanofi Completed No outcome recorded
Phase 23 trials
Phase 2 NCT01854047 Background Jun 2013 → Nov 2014 asthma Sanofi Completed No outcome recorded
Phase 2 NCT01312961 Background Mar 2011 → Oct 2012 asthma Sanofi Completed No outcome recorded
Phase 2 NCT00684827 Comparator Oct 2002 → Feb 2003 asthma Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 35 trials
Phase 3 NCT06040424 Comparator Sep 2023 → Jun 2024 chronic obstructive pulmonary disease Neutec Ar-Ge San ve Tic A.Ş Unknown No outcome recorded
Phase 3 NCT02528214 Background Oct 2015 → Sep 2017 asthma Sanofi Completed No outcome recorded
Phase 3 NCT02414854 Background Apr 2015 → Jul 2017 asthma Sanofi Completed No outcome recorded
Phase 3 NCT00583986 Background Sep 2005 → Jan 2006 asthma, chronic obstructive pulmonary disease Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 3 NCT00073840 Comparator Dec 2002 → Jun 2003 asthma Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 43 trials
Phase 4 NCT00819637 Comparator Jan → Nov 2009 acute asthma Henry Ford Health System Terminated No outcome recorded
Phase 4 NCT01151579 Comparator Dec 2008 → Nov 2009 chronic obstructive pulmonary disease, infectious disease with sepsis Fahim Khorfan, MD Completed No outcome recorded
Phase 4 NCT02170532 Comparator Jul 2007 → Jul 2009 asthma Duke University Completed No outcome recorded
Phase not applicable2 trials
NCT01833026 Background Mar 2013 → May 2016 chronic obstructive pulmonary disease University of Illinois at Chicago Completed No outcome recorded
NCT00583778 Background Aug 2004 → Nov 2008 asthma MetroHealth Medical Center Completed No outcome recorded

Evidence & citations 11 cited values

Every value below carries the sentence it was read from. 41 sources stand behind the page.

FieldValueCited text
Known as levalbuterol “three doses of nebulized 1.25 mg of levalbuterol alone every 20 minutes” NCT00583778
30

“Levosalbutamol/levalbuterolNCT01854047

NCT02414854

NCT02170532

NCT05173584

NCT00819637

NCT00583947

NCT00325767

NCT00268723

NCT00667407

NCT00685126

NCT00064389

NCT00685425

NCT00583986

NCT00684866

NCT00685022

NCT00685347

NCT00684827

NCT02528214

NCT01312961

NCT01656811

NCT02802111

NCT00665600

NCT00667797

NCT01833026

NCT00073814

NCT00124176

NCT00073827

NCT00073840

NCT01151579

NCT00809757

Known as ASF 1096 “Efficacy and Safety of ASF-1096 Cream 0.5% in the Treatment of Discoid Lupus Erythematosus (DLE) Lesions (2)” NCT00625157
3

“Efficacy and Safety of ASF-1096 Cream 0.5% in the Treatment of Discoid Lupus Erythematosus (DLE) Lesions” NCT00625521

ASF 1096 0.5 % cream applied twice daily” NCT00625521

NCT00625157

Known as Levalbuterol HCl Levalbuterol HCl Inhalation Solution” NCT00685126
2

“Drug: levalbuterol HClNCT00667797

“Drug: Levalbuterol HClNCT00665600

Known as Levalbuterol HFA MDI “Drug: Levalbuterol HFA MDINCT00685425
Known as levalbuterol tartrate HFA MDI “Drug: levalbuterol tartrate HFA MDINCT00064389
Known as Levosalbutamol “Drug: Levalbuterol/LevosalbutamolNCT02414854
8

“Levalbuterol/LevosalbutamolNCT02528214

NCT05366764

NCT01854047

NCT04446637

NCT06040424

NCT05890638

NCT00831376

NCT00830882

Known as R albuterol “Levalbuterol (R albuterol)” NCT00124176
Known as Xopenex “The spirometry test will be performed with a breathing medication called Levalbuterol (Xopenex®).” NCT01833026
1

NCT00585039

Known as Xopenex HFA (levalbuterol tartrate)Inhalation Aerosol Xopenex HFA (levalbuterol tartrate)Inhalation AerosolNCT00073840
Modality Other / unclassified “Beta-agonists like Levalbuterol and Albuterol are used in the treatment of Hyperkalemia.” PMID 41437987 Dec 2025
Route Inhaled “levalbuterol MDI 90 mcg QID” NCT00064389