Pilot Study of Betahistine Dihydrochloride in the Treatment of Major Depression With Atypical Features

Summary

The purpose of this study is to determine a dose of the investigational drug betahistine dihydrochloride that is both well tolerated and potentially effective in treating the symptoms of atypical depression. Atypical depression is characterized by the ability of the person's mood to improve temporarily in response to positive events, as well as features such as increased appetite, increased sleep and severe fatigue.

Timeline

Start

2007-07

Primary completion

2011-01

Completion

2011-01

Drugs

Indications