Drugs / Betahistine

Trials 16 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT05938517 Jun → Oct 2021 Meniere disease Ludwig-Maximilians - University of Munich Completed No outcome recorded
Phase 1 NCT01168336 Jul → Dec 2010 OBEcure Ltd. Completed No outcome recorded
Phase 1 NCT00852956 Feb → Apr 2009 OBEcure Ltd. Completed No outcome recorded
Phase 1 NCT00829881 Jan → Dec 2009 attention deficit-hyperactivity disorder P2D, Inc. Completed No outcome recorded
Phase 1 NCT00459992 Apr 2007 → Feb 2011 obesity disorder Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Completed No outcome recorded
Phase 27 trials
Phase 2 NCT07567274 May → Jul 2026 overdue tinnitus Leading Edge Clinic Enrolling by invitation No outcome recorded
Phase 2 NCT03908567 Jul 2019 → Mar 2022 peripheral vertigo Auris Medical AG Completed No outcome recorded
Phase 2 NCT00748436 Sep 2008 → Apr 2009 obesity disorder OBEcure Ltd. Completed No outcome recorded
Phase 2 NCT00585585 Jul 2007 → Jan 2011 atypical depressive disorder University of Cincinnati Terminated No outcome recorded
Phase 2 NCT00466869 May → Sep 2007 hyperlipidemia OBEcure Ltd. Terminated No outcome recorded
Phase 2 NCT00428168 Mar 2007 → Aug 2008 OBEcure Ltd. Terminated No outcome recorded
Phase 2 NCT00409305 Jan → Jun 2007 obesity disorder OBEcure Ltd. Completed No outcome recorded
Phase 42 trials
Phase 4 NCT01468285 Feb 2012 → Apr 2013 Abbott Products Completed No outcome recorded
Phase 4 NCT00160238 Jan 2003 → ? Meniere disease Solvay Pharmaceuticals Completed No outcome recorded
Phase not applicable2 trials
NCT03624283 Sep 2018 → Dec 2019 vestibular disorder Eye & ENT Hospital of Fudan University Unknown No outcome recorded
NCT02026778 Dec 2013 → Nov 2014 Yonsei University Completed No outcome recorded
Also used as a comparator or background therapy in 6 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT06001593 Background Sep 2023 → Nov 2025 overdue Meniere disease Seoul National University Hospital Recruiting No outcome recorded
Phase 22 trials
Phase 2 NCT06544434 Background May 2021 → Sep 2024 overdue Meniere disease Beijing Tongren Hospital Recruiting No outcome recorded
Phase 2 NCT00709202 Comparator Jul 2008 → May 2016 autism spectrum disorder, bipolar I disorder, bipolar II disorder, schizoaffective disorder +2 Nathan Kline Institute for Psychiatric Research Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT07435090 Comparator Mar 2026 → Dec 2027 expected peripheral vertigo Shi Tianming Not yet recruiting No outcome recorded
Phase 41 trial
Phase 4 NCT07075289 Comparator Apr → Aug 2024 benign paroxysmal positional vertigo Universitas Sebelas Maret Completed No outcome recorded
Phase not applicable1 trial
NCT07334002 Comparator Mar → May 2026 overdue tinnitus Sisli Hamidiye Etfal Training and Research Hospital Not yet recruiting No outcome recorded

Evidence & citations 9 cited values

Every value below carries the sentence it was read from. 22 sources stand behind the page.

FieldValueCited text
Known as Betahistine “Nasal spray solution with 5 mg/mL betahistine dihydrochloride. Administered three times daily as 1 spray per nostril. Total daily dose is 3 mg betahistine dihydrochloride.” NCT03908567
18

NCT06544434

NCT01168336

NCT00466869

NCT05938517

NCT06001593

NCT07567274

NCT00709202

NCT07334002

NCT00585585

NCT00409305

NCT02026778

NCT03624283

NCT00428168

NCT00459992

NCT00829881

NCT00160238

NCT07075289

NCT00852956

Known as Betahistine dihydrochloride “Drug: Betahistine dihydrochlorideNCT05938517
2

NCT00748436

NCT01468285

Known as Betahistine Mesylate Betahistine Mesylate tablet (Merislon, Eisai Co., Ltd., China) with the treatment of 6 mg, 3 times a day.” NCT06544434
2

“Comparing Oral Lumbrokinase DLBS1033 and Betahistine Mesylate in Benign Paroxysmal Positional Vertigo” NCT07075289

NCT07435090

Known as Betaserc “Betahistine 24 mg bid (Betaserc)” NCT07334002
1

“Betahistine 24 mg bid (Betaserc)” NCT00160238

Known as Merislon “Betahistine Mesylate tablet (Merislon, Eisai Co., Ltd., China) with the treatment of 6 mg, 3 times a day.” NCT06544434
Known as MERTIGO SR “betahistine mesylate (12 mg, MERTIGO SR tablet, Dexa Medica b.i.d.) for a 14-day prospective observation period.” NCT07075289
Action Activate “Betahistine is a drug that activates histamine” NCT00829881
Modality Small molecule “a histamine analog long used for the treatment of Meniere's disease, betahistine, that shows promise in reversing the antihistaminergic effects thought to be involved in...” NCT00709202
Route Oral “Subjects take either betahistine (in one of three possible doses) or placebo capsules one time on the days of admission to the Clinical Center (day 1), three times on day 2 and...” NCT00459992