drugset / Trial / NCT07435090

Efficacy and Safety of Rimegepant for Acute Dizziness

NCT07435090

Phase 2/3 Not yet recruiting 370 enrolled Shi Tianming
RandomizedParallel-groupOpen-labelTreatment

Summary

This study aims to explore the efficacy and safety of rimegepant for acute dizziness, including vestibular migraine (VM) and benign recurrent vertigo (BRV), through a multicenter, randomized controlled clinical trial. This study addresses the urgent clinical need for effective therapies for acute dizziness. Additionally, we will dynamically observe the changes in calcitonin gene-related peptide (CGRP) levels before and after treatment and explore the predictive value of CGRP levels for treatment efficacy and the prognosis of recurrence in patients. This study aims to provide a scientific basis to improve clinical management strategies for acute dizziness.

Timeline

Start
2026-03-20
Primary completion
2027-12-31
Completion
2028-06-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Betahistine Small molecule 12 mg Oral
Subject Rimegepant Small molecule 75 mg Oral

Indications