drugset / Trial / NCT00586261
Does Thiazolidinedione Therapy Improve Endothelial Function and Preserve Renal Function
RandomizedParallel-groupTriple-blindTreatment
Summary
The hypothesis of the current proposal is that chronic pioglitazone therapy will result in improved endothelial function, decreased inflammation, and preservation of renal function in patients with CKD but without diabetes.
Timeline
- Start
- 2006-03
- Primary completion
- 2009-01
- Completion
- 2009-07
Outcome
Outcome not reported
Stopped (Enrollment): “Low enrollment because of the specifics of the inclusion criteria”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Pioglitazone | Small molecule | 30 mg | — |
| Comparator | Nitroglycerin | Unknown | 0.4 mg | Other |