drugset / Trial / NCT00586261

Does Thiazolidinedione Therapy Improve Endothelial Function and Preserve Renal Function

NCT00586261 ↗

Terminated 36 enrolled Mayo Clinic
RandomizedParallel-groupTriple-blindTreatment

Summary

The hypothesis of the current proposal is that chronic pioglitazone therapy will result in improved endothelial function, decreased inflammation, and preservation of renal function in patients with CKD but without diabetes.

Timeline

Start
2006-03
Primary completion
2009-01
Completion
2009-07

Outcome

Outcome not reported

Stopped (Enrollment): “Low enrollment because of the specifics of the inclusion criteria”

Drugs

EvaluationDrugModalityDoseRoute
Comparator Pioglitazone Small molecule 30 mg —
Comparator Nitroglycerin Unknown 0.4 mg Other