drugset / Trial / NCT00594191

Efficacy and Safety of Simvastatin in the Treatment of Portal Hypertension

NCT00594191

Phase 2 Completed 59 enrolled Hospital Clinic of Barcelona
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to evaluate the effects of continuous simvastatin administration on the hepatic venous pressure gradient (HVPG), as a surrogate marker of prognosis, and its safety in patients with cirrhosis and portal hypertension.

Timeline

Start
2004-03
Primary completion
2007-04
Completion
2007-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Simvastatin Small molecule 40 mg Oral