Role of Oral Chlorhexidine Gel in Prevention of Ventilator Associated Pneumonia

Phase 3 Completed 86 enrolled All India Institute of Medical Sciences

RandomizedParallel-groupTriple-blindPrevention

Summary

The purpose of this study is to determine if oral mucosal application of chlorhexidine gel will prevent the development of ventilator associated pneumonia in children.

Timeline

Start: 2007-11
Primary completion: 2009-04
Completion: 2009-04

Publications

Sebastian MR, Lodha R, Kapil A, Kabra SK. Oral mucosal decontamination with chlorhexidine for the prevention of ventilator-associated pneumonia in children - a randomized, controlled trial. Pediatr Crit Care Med. 2012 Sep;13(5):e305-10. doi: 10.1097/PCC.0b013e31824ea119.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Chlorhexidine	Small molecule	1 %	Oral

Indications

No indication recorded.