drugset / Trial / NCT00610077

Letrozole vs. Clomiphene Citrate in Patients With Anovulatory Infertility

NCT00610077

Phase 3 Completed 55 enrolled Sun Pharmaceutical Industries, Inc.
RandomizedParallel-groupOpen-labelTreatment

Summary

OBJECTIVE: To compare the effectiveness of letrozole and clomiphene citrate (CC) in patients with anovulatory infertility. DESIGN: Open, prospective, randomized, parallel group, multicentric, comparative trial. SETTING: Out patient clinics of infertility centers in India. PATIENT(S): Fifty-five patients with anovulatory infertility were recruited. Twenty-seven patients (59 cycles) were given letrozole and twenty-eight patients (68 cycles) were given CC. Both drugs were given orally on days 3-7 of menstrual cycle. INTERVENTION(S): Letrozole, CC, ovulation induction, vaginal micronized progesterone, IUI.

Timeline

Start
2004-12
Primary completion
2006-07
Completion
2006-07

Drugs

EvaluationDrugModalityDoseRoute
Comparator Clomiphene Other / unclassified 100 mg Oral
Comparator Clomiphene Other / unclassified 150 mg Oral
Subject Letrozole Other / unclassified 2.5 mg Oral

Indications