Clomiphene

also known as Clomiphene Citrate · Clomid · Clomifene Citrate · clomiphen citrate · Chloramiphene · Clomifene · Clomifeni citras · Clomifeno · +13 more

Other / unclassified targets ESR1

Developed for: polycystic ovary syndrome · infertility disorder · anovulation · female infertility · male infertility · hypogonadism, male · hypogonadotropic hypogonadism · ovarian dysfunction
+15 more
· ovarian hyperstimulation syndrome · pregnancy disorder · spermatogenic failure · acromegaly · hyperprolactinemia · hypogonadism · menstrual disorder · prolactin-producing pituitary gland adenoma · rotator cuff syndrome · substance-related disorder · azoospermia · endometriosis · female reproductive system disorder · obesity disorder · ovarian disorder
Investigated by: Ain Shams University · Mansoura University · Ain Shams Maternity Hospital · Assiut University · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · National Center for Research Resources (NCRR)
+70 more
· Rachel Mejia · University Magna Graecia · University of Illinois at Chicago · University of Sao Paulo · University of Virginia · Weill Medical College of Cornell University · Yazd Research & Clinical Center for Infertility · Ahmed Fathy Ali Mohamed Ghanem · Al-Thawra Modern General Hospital · Albany Medical College · American Diabetes Association · American Society for Reproductive Medicine · American University of Beirut Medical Center · Auckland Medical Research Foundation · Beijing Fengtai Hospital of Integrated Traditional and Western Medicine · Beijing First Hospital of integrated Chinese and Western Medicine · Beijing Hospital of Traditional Chinese Medicine · Beijing Obstetrics and Gynecology Hospital · Benha University · Bioroma · Dongzhimen Hospital, Beijing · Eugin · Federal University of São Paulo · Felipe Henning Gaia Duarte · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico · Fundacion Dexeus · HITEC-Institute of Medical Sciences · Hospices Civils de Lyon · IRCCS San Raffaele · Ibn Sina Hospital · Istituti Clinici Zucchi · Istituto Clinico Humanitas · Johns Hopkins University · Kufa University · Laboratory Corporation of America · Laylay Mohammed Khalleefah Alhibshi · Mansoura Integrated Fertility Center · Mayo Clinic · Menoufia Obstetrics and Gynecology Group · Mercia Barnes Trust of the Royal Australian and New Zealand College of Obstetricians and Gynaecologists · Milton S. Hershey Medical Center · Navy General Hospital, Beijing · Nova Clinic, Russia · Partnership for Clean Competition · RenJi Hospital · Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF) · Royan Institute · Sana'a University · Semnan University of Medical Sciences · Shaare Zedek Medical Center · Shakeela Ishrat · ShangHai Ji Ai Genetics & IVF Institute · Sheba Medical Center · Society for Reproductive Investigation · Sports Medicine Research and Testing Laboratory · State University of New York at Buffalo · Stuart Willick · Szeged University · The Egyptian IVF-ET Center · The University of Hong Kong · University Hospitals Cleveland Medical Center · University of Auckland, New Zealand · University of Chicago · University of Oklahoma · University of Southern California · University of Utah · University of Wisconsin, Madison · Xiyuan Hospital of China Academy of Chinese Medical Sciences · Yale University · Yazd Medical University

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

Milestone	Jurisdiction	Brand	Indication	Date	Sentence it was read from
Approved	US (FDA)	CLOMID	—	1967-02-01	fda.gov ↗

Trials 65 · started per year

today

US approved 1967

196619671968196919701971197219731974197519761977197819791980198119821983198419851986198719881989199019911992199319941995199619971998199920002001200220032004200520062007200820092010201120122013201420152016201720182019202020212022202320242025202620272028

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 01 trial
Phase 0	NCT04361175	Mar → Sep 2021	infertility disorder	Assiut University	Unknown	No outcome recorded
Phase 16 trials
Phase 1	NCT06813118	Jun 2024 → Mar 2025	polycystic ovary syndrome	HITEC-Institute of Medical Sciences	Completed	No outcome recorded
Phase 1	NCT04177693	Nov 2020 → Jan 2022	leiomyoma	Yale University	Completed	No outcome recorded
Phase 1	NCT03028532	Mar 2017 → Jan 2018	substance abuse	Stuart Willick	Completed	No outcome recorded
Phase 1	NCT02448459	May 2015 → Mar 2016	infertility disorder	University of Sao Paulo	Completed	No outcome recorded
Phase 1	NCT02024984	Nov 2013 → Jun 2014	polycystic ovary syndrome	Ain Shams Maternity Hospital	Unknown	No outcome recorded
Phase 1	NCT01289756	Dec 2009 → Nov 2014	anovulation	Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF)	Completed	No outcome recorded
Phase 1/21 trial
Phase 1/2	NCT01340521	Mar 1991 → Mar 1994	infertility disorder	Milton S. Hershey Medical Center	Completed	No outcome recorded
Phase 29 trials
Phase 2	NCT04944836	Mar 2023 → Jul 2028 expected	rotator cuff syndrome	University of Utah	Recruiting	No outcome recorded
Phase 2	NCT05096169	May 2022 → Jan 2025	hypogonadism	Weill Medical College of Cornell University	Withdrawn	No outcome recorded
Phase 2	NCT03709849	Feb 2019 → Mar 2020	anovulation, hyperprolactinemia, menstrual disorder, ovarian dysfunction +1	Xiyuan Hospital of China Academy of Chinese Medical Sciences	Unknown	No outcome recorded
Phase 2	NCT02523898	Nov 2015 → Apr 2022	polycystic ovary syndrome	Semnan University of Medical Sciences	Terminated	No outcome recorded
Phase 2	NCT03933618	Apr 2015 → Mar 2017	hypogonadism, male	Albany Medical College	Completed	No outcome recorded
Phase 2	NCT01880086	Aug 2013 → Mar 2016	hypogonadism, male, male infertility, substance-related disorder	Weill Medical College of Cornell University	Completed	No outcome recorded
Phase 2	NCT02274311	Jan 2011 → Oct 2014	acromegaly	Felipe Henning Gaia Duarte	Completed	No outcome recorded
Phase 2	NCT01155518	Jun 2010 → Dec 2013	hypogonadotropic hypogonadism, type 2 diabetes mellitus	State University of New York at Buffalo	Terminated	No outcome recorded
Phase 2	NCT00697814	Jun 2004 → Jun 2005	hypogonadotropic hypogonadism, prolactin-producing pituitary gland adenoma	Federal University of São Paulo	Completed	No outcome recorded
Phase 2/32 trials
Phase 2/3	NCT03549741	Jul 2018 → Jun 2019	infertility disorder	Assiut University	Unknown	No outcome recorded
Phase 2/3	NCT03770026	Jan 2018 → Jan 2019	anovulation	Benha University	Completed	No outcome recorded
Phase 37 trials
Phase 3	NCT03615547	Jan 2026 → Jan 2029	spermatogenic failure	Hospices Civils de Lyon	Withdrawn	No outcome recorded
Phase 3	NCT07616973	May 2023 → May 2026 overdue	female infertility	Sana'a University	Active not recruiting	No outcome recorded
Phase 3	NCT06564961	Jul 2022 → Jun 2023	spermatogenic failure	Shakeela Ishrat	Completed	No outcome recorded
Phase 3	NCT02255578	Sep 2014 → Sep 2017	polycystic ovary syndrome	Sheba Medical Center	Unknown	No outcome recorded
Phase 3	NCT02732808	Sep 2014 → Apr 2016	female infertility	Royan Institute	Completed	No outcome recorded
Phase 3	NCT01008319	Oct 2009 → Nov 2015	anovulation, ovarian dysfunction	University of Oklahoma	Completed	No outcome recorded
Phase 3	NCT00068861	Nov 2002 → Feb 2006	female infertility, polycystic ovary syndrome, pregnancy disorder	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	Completed	No outcome recorded
Phase 420 trials
Phase 4	NCT06701071	Jun 2025 → Jun 2028 expected	female infertility	University of Southern California	Recruiting	No outcome recorded
Phase 4	NCT07523022	Sep 2024 → Sep 2026 expected	male infertility	Szeged University	Enrolling by invitation	No outcome recorded
Phase 4	NCT04157725	Jun 2023 → Jan 2025	infertility disorder, polycystic ovary syndrome	American University of Beirut Medical Center	Unknown	No outcome recorded
Phase 4	NCT04983173	Nov 2021 → Mar 2026	infertility disorder	Fundacion Dexeus	Completed	No outcome recorded
Phase 4	NCT05206448	Oct 2020 → Apr 2024 overdue	infertility disorder, polycystic ovary syndrome	Rachel Mejia	Active not recruiting	No outcome recorded
Phase 4	NCT03989024	Jul 2019 → Dec 2020	anovulation, infertility disorder, polycystic ovary syndrome	RenJi Hospital	Unknown	No outcome recorded
Phase 4	NCT03400722	Dec 2017 → Aug 2018	female infertility, ovarian hyperstimulation syndrome	Nova Clinic, Russia	Unknown	No outcome recorded
Phase 4	NCT03309436	Aug 2017 → Jun 2018	female infertility	ShangHai Ji Ai Genetics & IVF Institute	Unknown	No outcome recorded
Phase 4	NCT02802865	Aug 2016 → May 2018	infertility disorder, polycystic ovary syndrome	Rachel Mejia	Completed	No outcome recorded
Phase 4	NCT02479256	Jun 2015 → May 2016	polycystic ovary syndrome	Ain Shams University	Completed	No outcome recorded
Phase 4	NCT02288143	Jan → Mar 2015	infertility disorder	University of Sao Paulo	Completed	No outcome recorded
Phase 4	NCT02575248	Oct 2014 → Jul 2017	female infertility	Ain Shams University	Unknown	No outcome recorded
Phase 4	NCT02201914	Jan → Oct 2014	—	Bioroma	Unknown	No outcome recorded
Phase 4	NCT01791751	Jun 2012 → Feb 2013	female infertility	Eugin	Completed	No outcome recorded
Phase 4	NCT01529177	Feb 2012 → Sep 2016	male infertility	The Egyptian IVF-ET Center	Unknown	No outcome recorded
Phase 4	NCT01213147	Apr → Aug 2009	pregnancy disorder	Yazd Medical University	Completed	No outcome recorded
Phase 4	NCT00830492	Jan → Dec 2008	ovarian hyperstimulation syndrome	Yazd Research & Clinical Center for Infertility	Completed	No outcome recorded
Phase 4	NCT00471523	May 2006 → Mar 2007	anovulation, infertility disorder, polycystic ovary syndrome	University Magna Graecia	Completed	No outcome recorded
Phase 4	NCT00795808	Aug 2003 → Oct 2008	polycystic ovary syndrome	University of Auckland, New Zealand	Completed	No outcome recorded
Phase 4	NCT00558077	Feb 2003 → Oct 2005	anovulation, infertility disorder, polycystic ovary syndrome	University Magna Graecia	Completed	No outcome recorded

Phase not applicable19 trials
—	NCT04052607	Sep 2019 → Apr 2020	infertility disorder	Ibn Sina Hospital	Terminated	No outcome recorded
—	NCT04619914	Mar → Jul 2019	—	Laylay Mohammed Khalleefah Alhibshi	Completed	No outcome recorded
—	NCT03316469	Jul → Oct 2018	polycystic ovary syndrome	Ain Shams University	Unknown	No outcome recorded
—	NCT03178500	Feb 2017 → Jul 2018	polycystic ovary syndrome	Ain Shams Maternity Hospital	Unknown	No outcome recorded
—	NCT02775877	May 2016 → Jun 2019	female infertility	Navy General Hospital, Beijing	Unknown	No outcome recorded
—	NCT02647424	Dec 2015 → Dec 2017	infertility disorder, polycystic ovary syndrome	The University of Hong Kong	Unknown	No outcome recorded
—	NCT02377479	Mar 2015 → Mar 2017	infertility disorder	University Hospitals Cleveland Medical Center	Withdrawn	No outcome recorded
—	NCT01718444	Mar 2015 → Jun 2016	infertility disorder, polycystic ovary syndrome	University of Illinois at Chicago	Terminated	No outcome recorded
—	NCT02544776	Jan → Aug 2015	anovulation	Ahmed Fathy Ali Mohamed Ghanem	Completed	No outcome recorded
—	NCT02269306	Jan 2011 → Jan 2013	anovulation	Menoufia Obstetrics and Gynecology Group	Completed	No outcome recorded
—	NCT01953796	May 2010 → Jan 2011	polycystic ovary syndrome	Kufa University	Completed	No outcome recorded
—	NCT01910766	Jan 2010 → Jan 2013	polycystic ovary syndrome	Mansoura University	Completed	No outcome recorded
—	NCT01212263	Jan 2010 → Sep 2012	polycystic ovary syndrome	Mansoura Integrated Fertility Center	Completed	No outcome recorded
—	NCT01389713	Sep 2008 → Dec 2010	infertility disorder	Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico	Completed	No outcome recorded
—	NCT01157312	Aug 2008 → Apr 2010	polycystic ovary syndrome	Mansoura University	Completed	No outcome recorded
—	NCT00449514	May 2007 → ?	infertility disorder	Shaare Zedek Medical Center	Unknown	No outcome recorded
—	NCT00969631	Sep 2005 → Feb 2009	polycystic ovary syndrome	Mansoura University	Completed	No outcome recorded
—	NCT00005104	Jan 2000 → ?	hyperinsulinism, polycystic ovary syndrome	National Center for Research Resources (NCRR)	Completed	No outcome recorded
—	NCT00005654	Jan 2000 → ?	hyperinsulinism, polycystic ovary syndrome	National Center for Research Resources (NCRR)	Completed	No outcome recorded

Also used as a comparator or background therapy in 88 trials

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 03 trials
Phase 0	NCT03681197 Comparator	Jun 2018 → Apr 2019	infertility disorder	Elham Raafat	Unknown	No outcome recorded
Phase 0	NCT03566225 Comparator	Jan 2018 → Feb 2021	—	Ain Shams University	Completed	No outcome recorded
Phase 0	NCT01909141 Comparator	Aug 2013 → Feb 2014	infertility disorder, polycystic ovary syndrome	Cairo University	Completed	No outcome recorded
Phase 11 trial
Phase 1	NCT03755037 Comparator	Jan 2017 → Apr 2018	female infertility	Nesreen Abdel Fattah Abdullah Shehata	Completed	No outcome recorded
Phase 1/22 trials
Phase 1/2	NCT04916925 Background	Aug → Sep 2021	letrozole toxicity, polycystic ovary syndrome, vitamin D deficiency	Ain Shams University	Unknown	No outcome recorded
Phase 1/2	NCT00947713 Comparator	Aug 2009 → Aug 2010	gonadal disorder	Royan Institute	Completed	No outcome recorded
Phase 214 trials
Phase 2	NCT05231980 Background	Jun 2022 → May 2023	polycystic ovary syndrome	Ain Shams University	Completed	No outcome recorded
Phase 2	NCT03245827 Comparator	Apr 2019 → Oct 2021	hypogonadotropic hypogonadism	Sandeep Singh Dhindsa, M.D., F.A.C.E	Terminated	No outcome recorded
Phase 2	NCT03674385 Background	Jul 2018 → Mar 2019	polycystic ovary syndrome	Ain Shams University	Completed	No outcome recorded
Phase 2	NCT02656121 Background	Feb 2016 → Nov 2018	polycystic ovary syndrome	Ain Shams University	Completed	No outcome recorded
Phase 2	NCT02663830 Comparator	Jan 2016 → Jan 2017	anovulation	Ain Shams University	Completed	No outcome recorded
Phase 2	NCT02551367 Comparator	Oct 2015 → May 2016	anovulation, polycystic ovary syndrome	mostafa gomaa hamid halawa	Unknown	No outcome recorded
Phase 2	NCT02644304 Comparator	May 2015 → Oct 2016	female reproductive system disorder	Woman's Health University Hospital, Egypt	Unknown	No outcome recorded
Phase 2	NCT02380755 Comparator	Apr 2015 → Jan 2017	hypogonadism, male, obesity disorder	University of Sao Paulo	Completed	No outcome recorded
Phase 2	NCT02562664 Comparator	Jan → Jun 2014	polycystic ovary syndrome	Assiut University	Completed	No outcome recorded
Phase 2	NCT01904734 Comparator	Oct 2012 → Oct 2018	hypogonadism, male	Phoenix VA Health Care System	Completed	No outcome recorded
Phase 2	NCT00796289 Comparator	Feb → Dec 2009	infertility disorder	Ferring Pharmaceuticals	Completed	No outcome recorded
Phase 2	NCT01232075 Comparator	Sep 2008 → Nov 2010	infertility disorder	Cairo University	Completed	No outcome recorded
Phase 2	NCT00844350 Comparator	Oct 2006 → Sep 2007	ovarian disorder	Tabriz University	Completed	No outcome recorded
Phase 2	NCT00213148 Comparator	Mar 2005 → Dec 2007	anovulation	EMD Serono	Completed	No outcome recorded

Phase 2/37 trials
Phase 2/3	NCT05846906 Background	Oct 2021 → Apr 2022	female infertility	Beni-Suef University	Completed	No outcome recorded
Phase 2/3	NCT04870502 Comparator	Apr 2019 → Jul 2020	polycystic ovary syndrome	Saudi German Hospital - Madinah	Completed	No outcome recorded
Phase 2/3	NCT05702957 Comparator	Sep 2016 → Oct 2019	female infertility, polycystic ovary syndrome	Services Institute of Medical Sciences, Pakistan	Completed	No outcome recorded
Phase 2/3	NCT02775734 Comparator	May 2016 → Mar 2017	polycystic ovary syndrome	Ain Shams University	Completed	No outcome recorded
Phase 2/3	NCT02237755 Comparator	Oct → Nov 2014	female infertility	University of Athens	Unknown	No outcome recorded
Phase 2/3	NCT02381184 Comparator	Jun 2014 → Jul 2016	infertility disorder	Benha University	Completed	No outcome recorded
Phase 2/3	NCT00296465 Comparator	Feb → Nov 2005	female infertility	Ferring Pharmaceuticals	Completed	No outcome recorded

Phase 310 trials
Phase 3	NCT03059173 Background	Sep 2023 → Sep 2027 expected	polycystic ovary syndrome	University Hospital, Lille	Recruiting	No outcome recorded
Phase 3	NCT03396380 Comparator	Jul 2017 → Mar 2018	female infertility	Ain Shams University	Unknown	No outcome recorded
Phase 3	NCT03241472 Comparator	Feb 2016 → May 2017	infertility disorder	Assiut University	Completed	No outcome recorded
Phase 3	NCT02264847 Comparator	Oct 2014 → Apr 2017	anovulation	Cairo University	Unknown	No outcome recorded
Phase 3	NCT01638988 Comparator	Sep → Nov 2013	diabetes mellitus, polycystic ovary syndrome	Clinique Ovo	Withdrawn	No outcome recorded
Phase 3	NCT01044862 Comparator	Jun 2010 → Oct 2013	infertility disorder, pregnancy disorder	Yale University	Completed	No outcome recorded
Phase 3	NCT00719186 Comparator	Feb 2009 → May 2013	polycystic ovary syndrome, pregnancy disorder	Yale University	Completed	No outcome recorded
Phase 3	NCT00427700 Comparator	Aug 2008 → Aug 2009	polycystic ovary syndrome	Hospital de Clinicas de Porto Alegre	Completed	No outcome recorded
Phase 3	NCT00610077 Comparator	Dec 2004 → Jul 2006	infertility disorder	Sun Pharmaceutical Industries, Inc.	Completed	No outcome recorded
Phase 3	NCT00413179 Background	Dec 1997 → Apr 2003	anovulation, infertility disorder, polycystic ovary syndrome	59th Medical Wing	Completed	No outcome recorded

Phase 427 trials
Phase 4	NCT07462065 Comparator	Mar → Jun 2026 overdue	female infertility	PAEC General Hospital, Islamabad	Recruiting	No outcome recorded
Phase 4	NCT06178523 Comparator	Jan → Dec 2024	infertility disorder	Batterjee Medical College	Completed	No outcome recorded
Phase 4	NCT05753098 Background	Jan 2021 → Jan 2023	female infertility	Beni-Suef University	Completed	No outcome recorded
Phase 4	NCT04306692 Comparator	Jul 2020 → Apr 2021	female infertility, polycystic ovary syndrome	University Hospital, Ghent	Terminated	No outcome recorded
Phase 4	NCT04302532 Background	Jul → Sep 2020	—	Karachi Medical and Dental College	Completed	No outcome recorded
Phase 4	NCT04331197 Comparator	May 2020 → May 2021	female infertility	Cairo University	Unknown	No outcome recorded
Phase 4	NCT04210765 Comparator	Aug 2019 → May 2020	anovulation, infertility disorder	Bagcilar Training and Research Hospital	Completed	No outcome recorded
Phase 4	NCT04010942 Comparator	Apr → Dec 2018	polycystic ovary syndrome, vitamin D deficiency	Ain Shams University	Completed	No outcome recorded
Phase 4	NCT03806036 Comparator	Jan 2018 → Feb 2019	polycystic ovary syndrome	Cairo University	Unknown	No outcome recorded
Phase 4	NCT02690870 Comparator	Jan 2017 → May 2018	infertility disorder	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Unknown	No outcome recorded
Phase 4	NCT02330757 Comparator	Oct 2016 → Dec 2024	infertility disorder	Mansoura University	Unknown	No outcome recorded
Phase 4	NCT02890238 Comparator	Aug 2016 → Oct 2019	female infertility	Cairo University	Unknown	No outcome recorded
Phase 4	NCT02436226 Comparator	Mar 2016 → Jan 2023	female infertility, polycystic ovary syndrome	Mohamed Sayed Abdelhafez	Completed	No outcome recorded
Phase 4	NCT03630341 Background	Feb 2016 → Mar 2018	polycystic ovary syndrome	Assiut University	Completed	No outcome recorded
Phase 4	NCT02344888 Comparator	Feb 2015 → Jan 2019	infertility disorder, polycystic ovary syndrome	Mahmoud Thabet	Unknown	No outcome recorded
Phase 4	NCT02186782 Comparator	Jun 2014 → Jul 2018	anovulation, infertility disorder	Maher elesawi kamel elesawi	Unknown	No outcome recorded
Phase 4	NCT01577472 Comparator	Aug 2013 → Nov 2017	female infertility, ovarian dysfunction	University Hospital, Basel, Switzerland	Completed	No outcome recorded
Phase 4	NCT02352597 Comparator	Jan 2013 → Jan 2015	polycystic ovary syndrome	Cairo University	Completed	No outcome recorded
Phase 4	NCT01219101 Background	Mar 2011 → Nov 2012	infertility disorder	Royan Institute	Completed	No outcome recorded
Phase 4	NCT01921166 Comparator	Jan → Nov 2011	infertility disorder	Wake Forest University Health Sciences	Completed	No outcome recorded
Phase 4	NCT00502229 Comparator	Jan 2010 → Jan 2011	infertility disorder, polycystic ovary syndrome	University Magna Graecia	Withdrawn	No outcome recorded
Phase 4	NCT02638285 Background	Jan → Aug 2009	pregnancy disorder	Shiraz University of Medical Sciences	Completed	No outcome recorded
Phase 4	NCT00835744 Comparator	Aug 2008 → Mar 2012	infertility disorder	University Hospital Brussels	Completed	No outcome recorded
Phase 4	NCT00501839 Comparator	Aug 2008 → Sep 2010	infertility disorder, polycystic ovary syndrome	University Magna Graecia	Withdrawn	No outcome recorded
Phase 4	NCT01004068 Comparator	Feb 2008 → Oct 2009	anovulation, polycystic ovary syndrome	University Magna Graecia	Completed	No outcome recorded
Phase 4	NCT00478504 Comparator	May 2007 → Jun 2014	infertility disorder, polycystic ovary syndrome	University of Nottingham	Completed	No outcome recorded
Phase 4	NCT00461643 Comparator	Jan 2007 → Dec 2015	polycystic ovary syndrome	University Magna Graecia	Unknown	No outcome recorded

Phase not applicable24 trials
—	NCT07568574 Background	Mar 2026 → May 2028 expected	—	Enhanced Emirates Limited	Enrolling by invitation	No outcome recorded
—	NCT06635538 Background	Oct 2024 → Apr 2025 overdue	female infertility	Fundacion Dexeus	Recruiting	No outcome recorded
—	NCT06507332 Comparator	Mar → Sep 2024	polycystic ovary syndrome	Egymedicalpedia	Unknown	No outcome recorded
—	NCT05670795 Comparator	Jan 2023 → May 2024	infertility disorder	Bezmialem Vakif University	Unknown	No outcome recorded
—	NCT07398924 Background	Jan 2022 → Jun 2023	anovulation, female infertility	Yuzuncu Yil University	Completed	No outcome recorded
—	NCT05106712 Comparator	Nov 2021 → Jul 2023	female infertility, polycystic ovary syndrome, vitamin D deficiency	Umm Al-Qura University	Unknown	No outcome recorded
—	NCT05089344 Background	Oct 2021 → Oct 2022	female infertility	Ain Shams Maternity Hospital	Unknown	No outcome recorded
—	NCT04170439 Background	Nov 2019 → May 2020	—	Aljazeera Hospital	Completed	No outcome recorded
—	NCT03398993 Comparator	Jan → Dec 2018	infertility disorder	Cairo University	Unknown	No outcome recorded
—	NCT03301233 Background	Nov 2017 → Jul 2018	—	Ain Shams University	Completed	No outcome recorded
—	NCT03476356 Background	Nov 2017 → Mar 2018	polycystic ovary syndrome	Ain Shams University	Completed	No outcome recorded
—	NCT02865681 Background	Jul 2016 → Jun 2017	infertility disorder	New Hope Fertility Center	Completed	No outcome recorded
—	NCT02137265 Comparator	Sep 2015 → Oct 2020	azoospermia, hypogonadism, male	University of Illinois at Chicago	Withdrawn	No outcome recorded
—	NCT02710981 Background	Jun 2015 → Jan 2016	anovulation	Assiut University	Completed	No outcome recorded
—	NCT02520505 Comparator	Apr 2015 → Dec 2017	endometriosis, female infertility	The Cleveland Clinic	Withdrawn	No outcome recorded
—	NCT02345837 Comparator	Feb 2014 → Sep 2016	—	Al Hayat National Hospital	Unknown	No outcome recorded
—	NCT02294773 Comparator	Oct 2013 → Sep 2015	infertility disorder	Midwest Fertility Specialists	Completed	No outcome recorded
—	NCT01793038 Comparator	Mar 2013 → Jun 2014	infertility disorder, polycystic ovary syndrome	Mansoura Integrated Fertility Center	Unknown	No outcome recorded
—	NCT01607320 Comparator	Jun 2012 → Mar 2013	polycystic ovary syndrome	Bruce Lessey	Terminated	No outcome recorded
—	NCT01291056 Comparator	Jan 2010 → May 2011	—	University of Utah	Completed	No outcome recorded
—	NCT01679574 Comparator	Jan 2009 → Jan 2012	polycystic ovary syndrome	Assiut University	Completed	No outcome recorded
—	NCT01334762 Comparator	May 2007 → Jun 2010	endometriosis	Mansoura University	Completed	No outcome recorded
—	NCT01008046 Background	Apr 2007 → Jun 2009	polycystic ovary syndrome	Mansoura University	Completed	No outcome recorded
—	NCT00911313 Comparator	Jun 2006 → Jan 2009	polycystic ovary syndrome	Mansoura University	Completed	No outcome recorded

Evidence & citations 26 cited values

Every value below carries the sentence it was read from. 158 sources stand behind the page.

Field	Value	Cited text
Known as	clomiphene	“100 mg clomiphene Citrate (Clomid , global Napi , Egypt) CC tablets taken from day 3 to day 7 of the cycle” NCT02562664 ↗ 31 “Drug: Clomiphene” NCT01679574 ↗ NCT00068861 ↗ NCT07568574 ↗ NCT00795808 ↗ NCT02274311 ↗ NCT01904734 ↗ NCT02294773 ↗ NCT04170439 ↗ NCT03245827 ↗ NCT01289756 ↗ NCT02802865 ↗ NCT01607320 ↗ NCT02137265 ↗ NCT01953796 ↗ NCT01793038 ↗ NCT03400722 ↗ NCT00697814 ↗ NCT02775877 ↗ NCT02638285 ↗ NCT04010942 ↗ NCT02377479 ↗ NCT03989024 ↗ NCT03933618 ↗ NCT01155518 ↗ NCT03476356 ↗ NCT01921166 ↗ NCT02663830 ↗ NCT01291056 ↗ NCT02647424 ↗ NCT02690870 ↗ NCT04306692 ↗
Known as	Chloramiphene	ChEMBL registry synonym — accepted as the source's own label CHEMBL2355051 ↗
Known as	Clomid	“All patients received 100 mg CC (Clomid®; Global Napi Pharmaceuticals, Cairo, Egypt) for 5 days starting from day 3 of spontaneous or induced menstruation.” NCT01157312 ↗ 16 “induction of ovulation with clomiphene citrate (Clomid®, Aventis) 50 mg tablet twice daily starting from the third day of menstrual cycle and for 5 days” PMID 32363556 ↗ May 2020 “Clomid 50 mg per day will be administered orally and human chorionic gonadotrophin ( choriomon ) 5000 IU will be administered IM once per week.” NCT01529177 ↗ “Thirty PCOS patients treated with 3 cycles of 100mg/day of Clomid (clomiphene citrate) on days 3 to 7 following an initial provera withdrawal” NCT01607320 ↗ “Clomiphene citrate(Clomid; Aventis pharma S.AE, Global Napi pharmaceuticals, Cairo, Egypt) 100 mg/day is administered from cycle day 3 to 7.” NCT01232075 ↗ “100 mg clomiphene Citrate (Clomid , global Napi , Egypt) CC tablets taken from day 3 to day 7 of the cycle” NCT02562664 ↗ “patients in either group received 100 mg CC (Clomid®; Global Napi Pharmaceuticals,Cairo, Egypt)” NCT01008046 ↗ “Clomiphene citrate 50 mg tab oral tablets(Clomid 50 mg tablets Global Napi , Egypt)” NCT01212263 ↗ “Clomiphene citrate (Clomid) is often used for assisted reproductive technologies” NCT06701071 ↗ “Clomid is the standard first drug of treatment for ovulation induction” NCT01793038 ↗ “Clomiphene citrate (clomid) (50mg) will be given for 5 days” NCT03178500 ↗ “oral Clomiphene Citrate (Clomid®) 150 mg/day for 5 days” NCT04157725 ↗ “clomiphene citrate (clomid 50mg ®, Sanofi aventis)” NCT03301233 ↗ NCT03755037 ↗ NCT04916925 ↗ NCT04619914 ↗ NCT03028532 ↗
Known as	Clomifene	ChEMBL registry synonym — accepted as the source's own label CHEMBL2355051 ↗
Known as	Clomifene Citrate	“clomifene citrate 50 mg three times daily” NCT04052607 ↗ 5 NCT03615547 ↗ NCT01791751 ↗ NCT02544776 ↗ NCT01389713 ↗ NCT00478504 ↗
Known as	Clomifeni citras	ChEMBL registry synonym — accepted as the source's own label CHEMBL2355051 ↗
Known as	Clomifeno	ChEMBL registry synonym — accepted as the source's own label CHEMBL2355051 ↗
Known as	clomiphen citrate	“100mg of clomiphencitrate(Serophene®) are added to a high dose of HMG (450 IU of Merional®) in the early follicular phase of the stimulation (day 3 to 7).” NCT01577472 ↗ 1 “Initial clomiphen citrate (CC) doses were 50 mg daily for 5 days starting on cycle day 3.” NCT02269306 ↗
Known as	Clomiphene Citrate	“OBJECTIVE: To evaluate pregnancy rates with letrozole and clomiphene citrate (CC) alone for superovulation in an intrauterine insemination program for women with recently...” PMID 22181973 ↗ Jan 2012 122 “Clomiphene citrate (Ovumid®, Iran Hormones Company) 25 mg/day with co-treatment of Letrozole (Letrofem®, Iran Hormones Company) 2.5 mg/day are given from cycle day 3 onwards.” NCT02732808 ↗ “Randomised controlled trial on the effect of clomiphene citrate and gonadotropin dose on ovarian response markers and IVF outcomes in poor responders.” PMID 33367742 ↗ Mar 2021 “Following ovulation or no response to increasing clomiphene-citrate doses, correlations between predictors and treatment responses were analyzed.” PMID 26848057 ↗ Dec 2015 “Comparison of Micro-dose Human Chorionic Gonadotropin (hCG) With HMG in PCOs Patients With Previous Clomiphene Citrate (CC)-Resistant Anovulation” NCT00947713 ↗ “Letrozole Versus Combined Metformin and Clomiphene Citrate for Ovulation Induction in Clomiphene-Resistant Women With Polycystic Ovary Syndrome” NCT00911313 ↗ “Thirty PCOS patients treated with 3 cycles of 100mg/day of Clomid (clomiphene citrate) on days 3 to 7 following an initial provera withdrawal” NCT01607320 ↗ “Combined Metformin and Clomiphene Citrate (CC) or Laparoscopic Ovarian Diathermy for Women With CC Resistant Polycystic Ovary Syndrome (PCOS)” NCT00969631 ↗ “Clomiphene citrate, a selective estrogen-receptor modulator that antagonizes the negative feedback of estrogen at the hypothalamus” NCT04361175 ↗ “Clomiphene citrate is a well-established agent that has been empirically used in cases of idiopathic oligospermia.” PMID 16291975 ↗ Nov 2005 “Clomiphene citrate (CC) is a commonly prescribed pharmacologic agent used to induce ovulation in women with PCOS.” NCT06507332 ↗ “Clomiphene citrate 100mg (2 tablets clomid 50mg each per day,from 2nd to 6th day of the cycle ) will be added” NCT04010942 ↗ “100 mg clomiphene Citrate (Clomid , global Napi , Egypt) CC tablets taken from day 3 to day 7 of the cycle” NCT02562664 ↗ “Clomiphene citrate, a SERM that increases luteinizing hormone and follicle stimulating hormone secretion” NCT02274311 ↗ “clomiphene citrate 50 mg tablets twice /day for 5 days plus 37.5 IU uFSH IM injections daily for 10 days” NCT01793038 ↗ “CLOMID (clomiphene citrate tablets USP) is an orally administered, nonsteroidal, ovulatory stimulant” NCT04619914 ↗ “Each tablet contains 50 mg of clomiphene citrate which means 33,9 mg of clomiphene.” NCT04306692 ↗ “Clomiphene citrate 50 mg tab oral tablets(Clomid 50 mg tablets Global Napi , Egypt)” NCT01212263 ↗ “Clomiphene citrate is a well known selective estrogen receptor modulator” NCT00697814 ↗ “Oral clomiphene citrate: 100 mg/day until the day of the triggering.” NCT02448459 ↗ “Oral clomiphene citrate: 100 mg/day until the day of the triggering.” NCT02288143 ↗ “N-acetyl cysteine and clomiphene citrate(CC)with combined metformin” NCT01008046 ↗ “patients received a 50-mg dose of clomiphene citrate.” PMID 26848057 ↗ Dec 2015 “clomiphene citrate (clomid 50mg ®, Sanofi aventis)” NCT03301233 ↗ “Clomiphene Citrate for induction of ovulation” NCT02656121 ↗ “Experimental: Clomiphene Citrate (CC) + rFSH” NCT04983173 ↗ “Drug: Clomiphene citrate” NCT01638988 ↗ “Clomiphene Citrate 25mg” NCT03933618 ↗ NCT04331197 ↗ NCT00835744 ↗ NCT01213147 ↗ NCT01004068 ↗ NCT05089344 ↗ NCT00413179 ↗ NCT03316469 ↗ NCT02380755 ↗ NCT00501839 ↗ NCT03566225 ↗ NCT00461643 ↗ NCT02479256 ↗ NCT03178500 ↗ NCT01008319 ↗ NCT04157725 ↗ NCT02330757 ↗ NCT01910766 ↗ NCT02575248 ↗ NCT01909141 ↗ NCT06178523 ↗ NCT03630341 ↗ NCT03681197 ↗ NCT03674385 ↗ NCT06564961 ↗ NCT02381184 ↗ NCT02523898 ↗ NCT05206448 ↗ NCT05096169 ↗ NCT00610077 ↗ NCT02186782 ↗ NCT00213148 ↗ NCT02865681 ↗ NCT03059173 ↗ NCT02890238 ↗ NCT05702957 ↗ NCT02551367 ↗ NCT02264847 ↗ NCT03309436 ↗ NCT03241472 ↗ NCT02024984 ↗ NCT01157312 ↗ NCT02255578 ↗ NCT06813118 ↗ NCT00471523 ↗ NCT04302532 ↗ NCT02520505 ↗ NCT01638988 ↗ NCT00830492 ↗ NCT01044862 ↗ NCT02644304 ↗ NCT00449514 ↗ NCT02344888 ↗ NCT07616973 ↗ NCT07398924 ↗ NCT07523022 ↗ NCT01880086 ↗ NCT02710981 ↗ NCT00502229 ↗ NCT05846906 ↗ NCT00296465 ↗ NCT01718444 ↗ NCT03549741 ↗ NCT02352597 ↗ NCT03396380 ↗ NCT00719186 ↗ NCT02775734 ↗ NCT03770026 ↗ NCT01232075 ↗ NCT07462065 ↗ NCT00427700 ↗ NCT05670795 ↗ NCT03806036 ↗ NCT00005104 ↗ NCT00796289 ↗ NCT02201914 ↗ NCT02436226 ↗ NCT06701071 ↗ NCT00844350 ↗ NCT01529177 ↗ NCT06635538 ↗ NCT04870502 ↗ NCT04210765 ↗ NCT04177693 ↗ NCT03398993 ↗ NCT05106712 ↗ NCT05231980 ↗ NCT01219101 ↗ NCT00005654 ↗ NCT04944836 ↗ NCT03709849 ↗ NCT02237755 ↗ NCT05753098 ↗ NCT00558077 ↗ NCT02345837 ↗ NCT01340521 ↗
Known as	Clomiphene citrate (1:1)	ChEMBL registry synonym — accepted as the source's own label CHEMBL2355051 ↗
Known as	Clophene	ChEMBL registry synonym — accepted as the source's own label CHEMBL2355051 ↗
Known as	Clostilbegyt	ChEMBL registry synonym — accepted as the source's own label CHEMBL2355051 ↗
Known as	Ikaclomine	ChEMBL registry synonym — accepted as the source's own label CHEMBL2355051 ↗
Known as	MER-41	ChEMBL registry synonym — accepted as the source's own label CHEMBL2355051 ↗
Known as	Milophene	ChEMBL registry synonym — accepted as the source's own label CHEMBL2355051 ↗
Known as	MRL-41	ChEMBL registry synonym — accepted as the source's own label CHEMBL2355051 ↗
Known as	NSC-35770	ChEMBL registry synonym — accepted as the source's own label CHEMBL2355051 ↗
Known as	Omifin	“CC 50 mg/day (Omifin®) + rFSH 150 IU (Ovaleap®)” NCT04983173 ↗
Known as	Ovumid	“Clomiphene citrate (Ovumid®, Iran Hormones Company) 25 mg/day with co-treatment of Letrozole (Letrofem®, Iran Hormones Company) 2.5 mg/day are given from cycle day 3 onwards.” NCT02732808 ↗
Known as	Pergotime	ChEMBL registry synonym — accepted as the source's own label CHEMBL2355051 ↗
Known as	Serophene	“100mg of clomiphencitrate(Serophene®) are added to a high dose of HMG (450 IU of Merional®) in the early follicular phase of the stimulation (day 3 to 7).” NCT01577472 ↗
Known as	Tecnovula	“clomiphene citrate 50 mg (Tecnovula®)” NCT05753098 ↗
Action	Activate	“Traditionally, clomiphene citrate, an estrogen receptor agonist, is the most used drug for this type of anovulation.” NCT00427700 ↗
Modality	Other / unclassified	“Clomiphene citrate, a selective estrogen receptor modulator (SERM) oral medication which inhibits estrogen effects (feedback) on the brain” NCT01880086 ↗
Route	Oral	“oral clomiphene citrate daily” NCT00005104 ↗
Target	ESR1	“Estrogen receptor alpha modulator” CHEMBL2355051 ↗