Clomiphene Citrate

also known as clomiphene · Clomid · Clomifene Citrate · clomiphen citrate · Omifin · Ovumid · Tecnovula

Developed for: polycystic ovary syndrome · infertility disorder · anovulation · female infertility · male infertility · hypogonadism, male · hypogonadotropic hypogonadism · ovarian dysfunction
+16 more
· ovarian hyperstimulation syndrome · pregnancy disorder · spermatogenic failure · acromegaly · hyperprolactinemia · hypogonadism · menstrual disorder · oligoasthenoteratozoospermia · prolactin-producing pituitary gland adenoma · rotator cuff syndrome · substance-related disorder · azoospermia · endometriosis · female reproductive system disorder · obesity disorder · ovarian disorder
Investigated by: Ain Shams University · Mansoura University · Ain Shams Maternity Hospital · Assiut University · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · National Center for Research Resources (NCRR)
+71 more
· Rachel Mejia · University Magna Graecia · University of Illinois at Chicago · University of Sao Paulo · University of Virginia · Weill Medical College of Cornell University · Yazd Research & Clinical Center for Infertility · Ahmed Fathy Ali Mohamed Ghanem · Al-Thawra Modern General Hospital · Albany Medical College · American Diabetes Association · American Society for Reproductive Medicine · American University of Beirut Medical Center · Auckland Medical Research Foundation · Beijing Fengtai Hospital of Integrated Traditional and Western Medicine · Beijing First Hospital of integrated Chinese and Western Medicine · Beijing Hospital of Traditional Chinese Medicine · Beijing Obstetrics and Gynecology Hospital · Benha University · Bioroma · Dongzhimen Hospital, Beijing · Eugin · Federal University of São Paulo · Felipe Henning Gaia Duarte · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico · Fundacion Dexeus · HITEC-Institute of Medical Sciences · Hamad Medical Corporation · Hospices Civils de Lyon · IRCCS San Raffaele · Ibn Sina Hospital · Istituti Clinici Zucchi · Istituto Clinico Humanitas · Johns Hopkins University · Kufa University · Laboratory Corporation of America · Laylay Mohammed Khalleefah Alhibshi · Mansoura Integrated Fertility Center · Mayo Clinic · Menoufia Obstetrics and Gynecology Group · Mercia Barnes Trust of the Royal Australian and New Zealand College of Obstetricians and Gynaecologists · Milton S. Hershey Medical Center · Navy General Hospital, Beijing · Nova Clinic, Russia · Partnership for Clean Competition · RenJi Hospital · Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF) · Royan Institute · Sana'a University · Semnan University of Medical Sciences · Shaare Zedek Medical Center · Shakeela Ishrat · ShangHai Ji Ai Genetics & IVF Institute · Sheba Medical Center · Society for Reproductive Investigation · Sports Medicine Research and Testing Laboratory · State University of New York at Buffalo · Stuart Willick · Szeged University · The Egyptian IVF-ET Center · The University of Hong Kong · University Hospitals Cleveland Medical Center · University of Auckland, New Zealand · University of Chicago · University of Oklahoma · University of Southern California · University of Utah · University of Wisconsin, Madison · Xiyuan Hospital of China Academy of Chinese Medical Sciences · Yale University · Yazd Medical University

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

Milestone	Jurisdiction	Brand	Indication	Date	Sentence it was read from
Approved	US (FDA)	CLOMID	—	1967-02-01	fda.gov ↗

Trials 66 · started per year

today

US approved 1967

1966196719681969197019711972197319741975197619771978197919801981198219831984198519861987198819891990199119921993199419951996199719981999200020012002200320042005200620072008200920102011201220132014201520162017201820192020202120222023202420252026202720282029

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 01 trial
Phase 0	NCT04361175	Mar → Sep 2021	infertility disorder	Assiut University	Unknown	No outcome recorded
Phase 16 trials · 1 missed
Phase 1	NCT06813118	Jun 2024 → Mar 2025	polycystic ovary syndrome	HITEC-Institute of Medical Sciences	Completed	No outcome recorded
Phase 1	NCT04177693	Nov 2020 → Jan 2022	leiomyoma	Yale University	Completed	Missed primary
Phase 1	NCT03028532	Mar 2017 → Jan 2018	substance abuse	Stuart Willick	Completed	No outcome recorded
Phase 1	NCT02448459	May 2015 → Mar 2016	infertility disorder	University of Sao Paulo	Completed	No outcome recorded
Phase 1	NCT02024984	Nov 2013 → Jun 2014	polycystic ovary syndrome	Ain Shams Maternity Hospital	Unknown	No outcome recorded
Phase 1	NCT01289756	Dec 2009 → Nov 2014	anovulation	Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF)	Completed	No outcome recorded
Phase 1/21 trial
Phase 1/2	NCT01340521	Mar 1991 → Mar 1994	infertility disorder	Milton S. Hershey Medical Center	Completed	No outcome recorded
Phase 29 trials
Phase 2	NCT04944836	Mar 2023 → Jul 2028 expected	rotator cuff syndrome	University of Utah	Recruiting	No outcome recorded
Phase 2	NCT05096169	May 2022 → Jan 2025	hypogonadism	Weill Medical College of Cornell University	Withdrawn	No outcome recorded Stop: Enrollment
Phase 2	NCT03709849	Feb 2019 → Mar 2020	anovulation, hyperprolactinemia, menstrual disorder, ovarian dysfunction +1	Xiyuan Hospital of China Academy of Chinese Medical Sciences	Unknown	No outcome recorded
Phase 2	NCT02523898	Nov 2015 → Apr 2022	polycystic ovary syndrome	Semnan University of Medical Sciences	Terminated	No outcome recorded
Phase 2	NCT03933618	Apr 2015 → Mar 2017	hypogonadism, male	Albany Medical College	Completed	No outcome recorded
Phase 2	NCT01880086	Aug 2013 → Mar 2016	hypogonadism, male, male infertility, substance-related disorder	Weill Medical College of Cornell University	Completed	No outcome recorded
Phase 2	NCT02274311	Jan 2011 → Oct 2014	acromegaly	Felipe Henning Gaia Duarte	Completed	No outcome recorded
Phase 2	NCT01155518	Jun 2010 → Dec 2013	hypogonadotropic hypogonadism, type 2 diabetes mellitus	State University of New York at Buffalo	Terminated	No outcome recorded Stop: Business
Phase 2	NCT00697814	Jun 2004 → Jun 2005	hypogonadotropic hypogonadism, prolactin-producing pituitary gland adenoma	Federal University of São Paulo	Completed	No outcome recorded
Phase 2/32 trials
Phase 2/3	NCT03549741	Jul 2018 → Jun 2019	infertility disorder	Assiut University	Unknown	No outcome recorded
Phase 2/3	NCT03770026	Jan 2018 → Jan 2019	anovulation	Benha University	Completed	No outcome recorded
Phase 37 trials · 1 met primary
Phase 3	NCT03615547	Jan 2026 → Jan 2029	spermatogenic failure	Hospices Civils de Lyon	Withdrawn	No outcome recorded
Phase 3	NCT07616973	May 2023 → May 2026 overdue	female infertility	Sana'a University	Active not recruiting	No outcome recorded
Phase 3	NCT06564961	Jul 2022 → Jun 2023	spermatogenic failure	Shakeela Ishrat	Completed	No outcome recorded
Phase 3	NCT02732808	Sep 2014 → Apr 2016	female infertility	Royan Institute	Completed	No outcome recorded
Phase 3	NCT02255578	Sep 2014 → Sep 2017	polycystic ovary syndrome	Sheba Medical Center	Unknown	No outcome recorded
Phase 3	NCT01008319	Oct 2009 → Nov 2015	anovulation, ovarian dysfunction	University of Oklahoma	Completed	No outcome recorded
Phase 3	NCT00068861	Nov 2002 → Feb 2006	female infertility, polycystic ovary syndrome, pregnancy disorder	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	Completed	Met primary
Phase 421 trials · 1 met primary · 1 missed
Phase 4	NCT07862725	Oct 2026 → Oct 2027 expected	oligoasthenoteratozoospermia	Hamad Medical Corporation	Not yet recruiting	No outcome recorded
Phase 4	NCT06701071	Jun 2025 → Jun 2028 expected	female infertility	University of Southern California	Recruiting	No outcome recorded
Phase 4	NCT07523022	Sep 2024 → Sep 2026 overdue	male infertility	Szeged University	Enrolling by invitation	No outcome recorded
Phase 4	NCT04157725	Jun 2023 → Jan 2025	infertility disorder, polycystic ovary syndrome	American University of Beirut Medical Center	Unknown	No outcome recorded
Phase 4	NCT04983173	Nov 2021 → Mar 2026	infertility disorder	Fundacion Dexeus	Completed	No outcome recorded
Phase 4	NCT05206448	Oct 2020 → Apr 2024 overdue	infertility disorder, polycystic ovary syndrome	Rachel Mejia	Active not recruiting	No outcome recorded
Phase 4	NCT03989024	Jul 2019 → Dec 2020	anovulation, infertility disorder, polycystic ovary syndrome	RenJi Hospital	Unknown	No outcome recorded
Phase 4	NCT03400722	Dec 2017 → Aug 2018	female infertility, ovarian hyperstimulation syndrome	Nova Clinic, Russia	Unknown	No outcome recorded
Phase 4	NCT03309436	Aug 2017 → Jun 2018	female infertility	ShangHai Ji Ai Genetics & IVF Institute	Unknown	No outcome recorded
Phase 4	NCT02802865	Aug 2016 → May 2018	infertility disorder, polycystic ovary syndrome	Rachel Mejia	Completed	Met primary
Phase 4	NCT02479256	Jun 2015 → May 2016	polycystic ovary syndrome	Ain Shams University	Completed	No outcome recorded
Phase 4	NCT02288143	Jan → Mar 2015	infertility disorder	University of Sao Paulo	Completed	No outcome recorded
Phase 4	NCT02575248	Oct 2014 → Jul 2017	female infertility	Ain Shams University	Unknown	No outcome recorded
Phase 4	NCT02201914	Jan → Oct 2014	—	Bioroma	Unknown	No outcome recorded
Phase 4	NCT01791751	Jun 2012 → Feb 2013	female infertility	Eugin	Completed	No outcome recorded
Phase 4	NCT01529177	Feb 2012 → Sep 2016	male infertility	The Egyptian IVF-ET Center	Unknown	No outcome recorded
Phase 4	NCT01213147	Apr → Aug 2009	pregnancy disorder	Yazd Medical University	Completed	No outcome recorded
Phase 4	NCT00830492	Jan → Dec 2008	ovarian hyperstimulation syndrome	Yazd Research & Clinical Center for Infertility	Completed	No outcome recorded
Phase 4	NCT00471523	May 2006 → Mar 2007	anovulation, infertility disorder, polycystic ovary syndrome	University Magna Graecia	Completed	No outcome recorded
Phase 4	NCT00795808	Aug 2003 → Oct 2008	polycystic ovary syndrome	University of Auckland, New Zealand	Completed	Missed primary
Phase 4	NCT00558077	Feb 2003 → Oct 2005	anovulation, infertility disorder, polycystic ovary syndrome	University Magna Graecia	Completed	No outcome recorded

Phase not applicable19 trials · 1 met primary · 1 missed
—	NCT04052607	Sep 2019 → Apr 2020	infertility disorder	Ibn Sina Hospital	Terminated	No outcome recorded
—	NCT04619914	Mar → Jul 2019	—	Laylay Mohammed Khalleefah Alhibshi	Completed	No outcome recorded
—	NCT03316469	Jul → Oct 2018	polycystic ovary syndrome	Ain Shams University	Unknown	No outcome recorded
—	NCT03178500	Feb 2017 → Jul 2018	polycystic ovary syndrome	Ain Shams Maternity Hospital	Unknown	No outcome recorded
—	NCT02775877	May 2016 → Jun 2019	female infertility	Navy General Hospital, Beijing	Unknown	No outcome recorded
—	NCT02647424	Dec 2015 → Dec 2017	infertility disorder, polycystic ovary syndrome	The University of Hong Kong	Unknown	No outcome recorded
—	NCT02377479	Mar 2015 → Mar 2017	infertility disorder	University Hospitals Cleveland Medical Center	Withdrawn	No outcome recorded
—	NCT01718444	Mar 2015 → Jun 2016	infertility disorder, polycystic ovary syndrome	University of Illinois at Chicago	Terminated	No outcome recorded
—	NCT02544776	Jan → Aug 2015	anovulation	Ahmed Fathy Ali Mohamed Ghanem	Completed	No outcome recorded
—	NCT02269306	Jan 2011 → Jan 2013	anovulation	Menoufia Obstetrics and Gynecology Group	Completed	No outcome recorded
—	NCT01953796	May 2010 → Jan 2011	polycystic ovary syndrome	Kufa University	Completed	No outcome recorded
—	NCT01910766	Jan 2010 → Jan 2013	polycystic ovary syndrome	Mansoura University	Completed	No outcome recorded
—	NCT01212263	Jan 2010 → Sep 2012	polycystic ovary syndrome	Mansoura Integrated Fertility Center	Completed	Met primary
—	NCT01389713	Sep 2008 → Dec 2010	infertility disorder	Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico	Completed	No outcome recorded
—	NCT01157312	Aug 2008 → Apr 2010	polycystic ovary syndrome	Mansoura University	Completed	Missed primary
—	NCT00449514	May 2007 → ?	infertility disorder	Shaare Zedek Medical Center	Unknown	No outcome recorded
—	NCT00969631	Sep 2005 → Feb 2009	polycystic ovary syndrome	Mansoura University	Completed	No outcome recorded
—	NCT00005654	Jan 2000 → ?	hyperinsulinism, polycystic ovary syndrome	National Center for Research Resources (NCRR)	Completed	No outcome recorded
—	NCT00005104	Jan 2000 → ?	hyperinsulinism, polycystic ovary syndrome	National Center for Research Resources (NCRR)	Completed	No outcome recorded

Comparator or background therapy87 trials
Phase 0	NCT03681197 Comparator	Jun 2018 → Apr 2019	infertility disorder	Elham Raafat	Unknown	No outcome recorded
Phase 0	NCT03566225 Comparator	Jan 2018 → Feb 2021	—	Ain Shams University	Completed	No outcome recorded
Phase 0	NCT01909141 Comparator	Aug 2013 → Feb 2014	infertility disorder, polycystic ovary syndrome	Cairo University	Completed	No outcome recorded
Phase 1	NCT03755037 Comparator	Jan 2017 → Apr 2018	female infertility	Nesreen Abdel Fattah Abdullah Shehata	Completed	No outcome recorded
Phase 1/2	NCT04916925 Background	Aug → Sep 2021	letrozole toxicity, polycystic ovary syndrome, vitamin D deficiency	Ain Shams University	Unknown	No outcome recorded
Phase 1/2	NCT00947713 Comparator	Aug 2009 → Aug 2010	gonadal disorder	Royan Institute	Completed	No outcome recorded
Phase 2	NCT05231980 Background	Jun 2022 → May 2023	polycystic ovary syndrome	Ain Shams University	Completed	No outcome recorded
Phase 2	NCT03245827 Comparator	Apr 2019 → Oct 2021	hypogonadotropic hypogonadism	Sandeep Singh Dhindsa, M.D., F.A.C.E	Terminated	No outcome recorded Stop: Enrollment
Phase 2	NCT03674385 Background	Jul 2018 → Mar 2019	polycystic ovary syndrome	Ain Shams University	Completed	No outcome recorded
Phase 2	NCT02656121 Background	Feb 2016 → Nov 2018	polycystic ovary syndrome	Ain Shams University	Completed	No outcome recorded
Phase 2	NCT02663830 Comparator	Jan 2016 → Jan 2017	anovulation	Ain Shams University	Completed	No outcome recorded
Phase 2	NCT02551367 Comparator	Oct 2015 → May 2016	anovulation, polycystic ovary syndrome	mostafa gomaa hamid halawa	Unknown	No outcome recorded
Phase 2	NCT02644304 Comparator	May 2015 → Oct 2016	female reproductive system disorder	Woman's Health University Hospital, Egypt	Unknown	No outcome recorded
Phase 2	NCT02380755 Comparator	Apr 2015 → Jan 2017	hypogonadism, male, obesity disorder	University of Sao Paulo	Completed	No outcome recorded
Phase 2	NCT02562664 Comparator	Jan → Jun 2014	polycystic ovary syndrome	Assiut University	Completed	No outcome recorded
Phase 2	NCT01904734 Comparator	Oct 2012 → Oct 2018	hypogonadism, male	Phoenix VA Health Care System	Completed	No outcome recorded
Phase 2	NCT00796289 Comparator	Feb → Dec 2009	infertility disorder	Ferring Pharmaceuticals	Completed	No outcome recorded
Phase 2	NCT01232075 Comparator	Sep 2008 → Nov 2010	infertility disorder	Cairo University	Completed	No outcome recorded
Phase 2	NCT00844350 Comparator	Oct 2006 → Sep 2007	ovarian disorder	Tabriz University	Completed	No outcome recorded
Phase 2	NCT00213148 Comparator	Mar 2005 → Dec 2007	anovulation	EMD Serono	Completed	No outcome recorded
Phase 2/3	NCT05846906 Background	Oct 2021 → Apr 2022	female infertility	Beni-Suef University	Completed	No outcome recorded
Phase 2/3	NCT04870502 Comparator	Apr 2019 → Jul 2020	polycystic ovary syndrome	Saudi German Hospital - Madinah	Completed	No outcome recorded
Phase 2/3	NCT05702957 Comparator	Sep 2016 → Oct 2019	female infertility, polycystic ovary syndrome	Services Institute of Medical Sciences, Pakistan	Completed	No outcome recorded
Phase 2/3	NCT02775734 Comparator	May 2016 → Mar 2017	polycystic ovary syndrome	Ain Shams University	Completed	No outcome recorded
Phase 2/3	NCT02237755 Comparator	Oct → Nov 2014	female infertility	University of Athens	Unknown	No outcome recorded
Phase 2/3	NCT02381184 Comparator	Jun 2014 → Jul 2016	infertility disorder	Benha University	Completed	No outcome recorded
Phase 2/3	NCT00296465 Comparator	Feb → Nov 2005	female infertility	Ferring Pharmaceuticals	Completed	No outcome recorded
Phase 3	NCT03059173 Background	Sep 2023 → Sep 2027 expected	polycystic ovary syndrome	University Hospital, Lille	Recruiting	No outcome recorded
Phase 3	NCT03396380 Comparator	Jul 2017 → Mar 2018	female infertility	Ain Shams University	Unknown	No outcome recorded
Phase 3	NCT03241472 Comparator	Feb 2016 → May 2017	infertility disorder	Assiut University	Completed	No outcome recorded
Phase 3	NCT02264847 Comparator	Oct 2014 → Apr 2017	anovulation	Cairo University	Unknown	No outcome recorded
Phase 3	NCT01638988 Comparator	Sep → Nov 2013	diabetes mellitus, polycystic ovary syndrome	Clinique Ovo	Withdrawn	No outcome recorded
Phase 3	NCT01044862 Comparator	Jun 2010 → Oct 2013	infertility disorder, pregnancy disorder	Yale University	Completed	No outcome recorded
Phase 3	NCT00719186 Comparator	Feb 2009 → May 2013	polycystic ovary syndrome, pregnancy disorder	Yale University	Completed	No outcome recorded
Phase 3	NCT00427700 Comparator	Aug 2008 → Aug 2009	polycystic ovary syndrome	Hospital de Clinicas de Porto Alegre	Completed	Missed primary
Phase 3	NCT00610077 Comparator	Dec 2004 → Jul 2006	infertility disorder	Sun Pharmaceutical Industries, Inc.	Completed	No outcome recorded
Phase 3	NCT00413179 Background	Dec 1997 → Apr 2003	anovulation, infertility disorder, polycystic ovary syndrome	59th Medical Wing	Completed	No outcome recorded
Phase 4	NCT07462065 Comparator	Mar → Jun 2026 overdue	female infertility	PAEC General Hospital, Islamabad	Recruiting	No outcome recorded
Phase 4	NCT06178523 Comparator	Jan → Dec 2024	infertility disorder	Batterjee Medical College	Completed	No outcome recorded
Phase 4	NCT05753098 Background	Jan 2021 → Jan 2023	female infertility	Beni-Suef University	Completed	No outcome recorded
Phase 4	NCT04306692 Comparator	Jul 2020 → Apr 2021	female infertility, polycystic ovary syndrome	University Hospital, Ghent	Terminated	No outcome recorded
Phase 4	NCT04302532 Background	Jul → Sep 2020	—	Karachi Medical and Dental College	Completed	No outcome recorded
Phase 4	NCT04331197 Comparator	May 2020 → May 2021	female infertility	Cairo University	Unknown	No outcome recorded
Phase 4	NCT04210765 Comparator	Aug 2019 → May 2020	anovulation, infertility disorder	Bagcilar Training and Research Hospital	Completed	No outcome recorded
Phase 4	NCT04010942 Comparator	Apr → Dec 2018	polycystic ovary syndrome, vitamin D deficiency	Ain Shams University	Completed	No outcome recorded
Phase 4	NCT03806036 Comparator	Jan 2018 → Feb 2019	polycystic ovary syndrome	Cairo University	Unknown	No outcome recorded
Phase 4	NCT02690870 Comparator	Jan 2017 → May 2018	infertility disorder	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Unknown	No outcome recorded
Phase 4	NCT02330757 Comparator	Oct 2016 → Dec 2024	infertility disorder	Mansoura University	Unknown	No outcome recorded
Phase 4	NCT02890238 Comparator	Aug 2016 → Oct 2019	female infertility	Cairo University	Unknown	No outcome recorded
Phase 4	NCT02436226 Comparator	Mar 2016 → Jan 2023	female infertility, polycystic ovary syndrome	Mohamed Sayed Abdelhafez	Completed	No outcome recorded
Phase 4	NCT03630341 Background	Feb 2016 → Mar 2018	polycystic ovary syndrome	Assiut University	Completed	No outcome recorded
Phase 4	NCT02344888 Comparator	Feb 2015 → Jan 2019	infertility disorder, polycystic ovary syndrome	Mahmoud Thabet	Unknown	No outcome recorded
Phase 4	NCT02186782 Comparator	Jun 2014 → Jul 2018	anovulation, infertility disorder	Maher elesawi kamel elesawi	Unknown	No outcome recorded
Phase 4	NCT02352597 Comparator	Jan 2013 → Jan 2015	polycystic ovary syndrome	Cairo University	Completed	No outcome recorded
Phase 4	NCT01219101 Background	Mar 2011 → Nov 2012	infertility disorder	Royan Institute	Completed	Met primary
Phase 4	NCT01921166 Comparator	Jan → Nov 2011	infertility disorder	Wake Forest University Health Sciences	Completed	No outcome recorded
Phase 4	NCT00502229 Comparator	Jan 2010 → Jan 2011	infertility disorder, polycystic ovary syndrome	University Magna Graecia	Withdrawn	No outcome recorded
Phase 4	NCT02638285 Background	Jan → Aug 2009	pregnancy disorder	Shiraz University of Medical Sciences	Completed	No outcome recorded
Phase 4	NCT00501839 Comparator	Aug 2008 → Sep 2010	infertility disorder, polycystic ovary syndrome	University Magna Graecia	Withdrawn	No outcome recorded
Phase 4	NCT00835744 Comparator	Aug 2008 → Mar 2012	infertility disorder	University Hospital Brussels	Completed	No outcome recorded
Phase 4	NCT01004068 Comparator	Feb 2008 → Oct 2009	anovulation, polycystic ovary syndrome	University Magna Graecia	Completed	No outcome recorded
Phase 4	NCT00478504 Comparator	May 2007 → Jun 2014	infertility disorder, polycystic ovary syndrome	University of Nottingham	Completed	No outcome recorded
Phase 4	NCT00461643 Comparator	Jan 2007 → Dec 2015	polycystic ovary syndrome	University Magna Graecia	Unknown	No outcome recorded
—	NCT07568574 Background	Mar 2026 → May 2028 expected	—	Enhanced Emirates Limited	Enrolling by invitation	No outcome recorded
—	NCT06635538 Background	Oct 2024 → Nov 2025	female infertility	Fundacion Dexeus	Completed	No outcome recorded
—	NCT06507332 Comparator	Mar → Sep 2024	polycystic ovary syndrome	Egymedicalpedia	Unknown	No outcome recorded
—	NCT05670795 Comparator	Jan 2023 → May 2024	infertility disorder	Bezmialem Vakif University	Unknown	No outcome recorded
—	NCT07398924 Background	Jan 2022 → Jun 2023	anovulation, female infertility	Yuzuncu Yil University	Completed	No outcome recorded
—	NCT05106712 Comparator	Nov 2021 → Jul 2023	female infertility, polycystic ovary syndrome, vitamin D deficiency	Umm Al-Qura University	Unknown	No outcome recorded
—	NCT05089344 Background	Oct 2021 → Oct 2022	female infertility	Ain Shams Maternity Hospital	Unknown	No outcome recorded
—	NCT04170439 Background	Nov 2019 → May 2020	—	Aljazeera Hospital	Completed	No outcome recorded
—	NCT03398993 Comparator	Jan → Dec 2018	infertility disorder	Cairo University	Unknown	No outcome recorded
—	NCT03476356 Background	Nov 2017 → Mar 2018	polycystic ovary syndrome	Ain Shams University	Completed	No outcome recorded
—	NCT03301233 Background	Nov 2017 → Jul 2018	—	Ain Shams University	Completed	No outcome recorded
—	NCT02865681 Background	Jul 2016 → Jun 2017	infertility disorder	New Hope Fertility Center	Completed	No outcome recorded
—	NCT02137265 Comparator	Sep 2015 → Oct 2020	azoospermia, hypogonadism, male	University of Illinois at Chicago	Withdrawn	No outcome recorded Stop: Business
—	NCT02710981 Background	Jun 2015 → Jan 2016	anovulation	Assiut University	Completed	No outcome recorded
—	NCT02520505 Comparator	Apr 2015 → Dec 2017	endometriosis, female infertility	The Cleveland Clinic	Withdrawn	No outcome recorded Stop: Enrollment
—	NCT02345837 Comparator	Feb 2014 → Sep 2016	—	Al Hayat National Hospital	Unknown	No outcome recorded
—	NCT02294773 Comparator	Oct 2013 → Sep 2015	infertility disorder	Midwest Fertility Specialists	Completed	No outcome recorded
—	NCT01793038 Comparator	Mar 2013 → Jun 2014	infertility disorder, polycystic ovary syndrome	Mansoura Integrated Fertility Center	Unknown	No outcome recorded
—	NCT01607320 Comparator	Jun 2012 → Mar 2013	polycystic ovary syndrome	Bruce Lessey	Terminated	No outcome recorded Stop: Enrollment
—	NCT01291056 Comparator	Jan 2010 → May 2011	—	University of Utah	Completed	No outcome recorded
—	NCT01679574 Comparator	Jan 2009 → Jan 2012	polycystic ovary syndrome	Assiut University	Completed	No outcome recorded
—	NCT01334762 Comparator	May 2007 → Jun 2010	endometriosis	Mansoura University	Completed	No outcome recorded
—	NCT01008046 Background	Apr 2007 → Jun 2009	polycystic ovary syndrome	Mansoura University	Completed	No outcome recorded
—	NCT00911313 Comparator	Jun 2006 → Jan 2009	polycystic ovary syndrome	Mansoura University	Completed	No outcome recorded

Press releases naming this drug 1 release

Date	Issuer	Release
2023-10-03	Cosette Pharmaceuticals, Inc.	Cosette Pharmaceuticals Partners With Mark Cuban Cost Plus Drug Company to Make CLOMID® More Affordable cosettepharma.com ↗

Evidence & citations 11 cited values

Every value below carries the sentence it was read from. 156 sources stand behind the page.

Field	Value	Cited text
Known as	Clomiphene citrate	“OBJECTIVE: To evaluate pregnancy rates with letrozole and clomiphene citrate (CC) alone for superovulation in an intrauterine insemination program for women with recently...” PMID 22181973 ↗ Jan 2012 122 “Clomiphene citrate (Ovumid®, Iran Hormones Company) 25 mg/day with co-treatment of Letrozole (Letrofem®, Iran Hormones Company) 2.5 mg/day are given from cycle day 3 onwards.” NCT02732808 ↗ “Following ovulation or no response to increasing clomiphene-citrate doses, correlations between predictors and treatment responses were analyzed.” PMID 26848057 ↗ Dec 2015 “Comparison of Micro-dose Human Chorionic Gonadotropin (hCG) With HMG in PCOs Patients With Previous Clomiphene Citrate (CC)-Resistant Anovulation” NCT00947713 ↗ “Letrozole Versus Combined Metformin and Clomiphene Citrate for Ovulation Induction in Clomiphene-Resistant Women With Polycystic Ovary Syndrome” NCT00911313 ↗ “Thirty PCOS patients treated with 3 cycles of 100mg/day of Clomid (clomiphene citrate) on days 3 to 7 following an initial provera withdrawal” NCT01607320 ↗ “Combined Metformin and Clomiphene Citrate (CC) or Laparoscopic Ovarian Diathermy for Women With CC Resistant Polycystic Ovary Syndrome (PCOS)” NCT00969631 ↗ “Clomiphene citrate, a selective estrogen-receptor modulator that antagonizes the negative feedback of estrogen at the hypothalamus” NCT04361175 ↗ “Clomiphene citrate is a well-established agent that has been empirically used in cases of idiopathic oligospermia.” PMID 16291975 ↗ Nov 2005 “Clomiphene citrate (CC) is a commonly prescribed pharmacologic agent used to induce ovulation in women with PCOS.” NCT06507332 ↗ “Clomiphene citrate 100mg (2 tablets clomid 50mg each per day,from 2nd to 6th day of the cycle ) will be added” NCT04010942 ↗ Show 112 more sources
Known as	Clomid	“All patients received 100 mg CC (Clomid®; Global Napi Pharmaceuticals, Cairo, Egypt) for 5 days starting from day 3 of spontaneous or induced menstruation.” NCT01157312 ↗ 16 “induction of ovulation with clomiphene citrate (Clomid®, Aventis) 50 mg tablet twice daily starting from the third day of menstrual cycle and for 5 days” PMID 32363556 ↗ May 2020 “Clomid 50 mg per day will be administered orally and human chorionic gonadotrophin ( choriomon ) 5000 IU will be administered IM once per week.” NCT01529177 ↗ “Thirty PCOS patients treated with 3 cycles of 100mg/day of Clomid (clomiphene citrate) on days 3 to 7 following an initial provera withdrawal” NCT01607320 ↗ “Clomiphene citrate(Clomid; Aventis pharma S.AE, Global Napi pharmaceuticals, Cairo, Egypt) 100 mg/day is administered from cycle day 3 to 7.” NCT01232075 ↗ “100 mg clomiphene Citrate (Clomid , global Napi , Egypt) CC tablets taken from day 3 to day 7 of the cycle” NCT02562664 ↗ “patients in either group received 100 mg CC (Clomid®; Global Napi Pharmaceuticals,Cairo, Egypt)” NCT01008046 ↗ “Clomiphene citrate 50 mg tab oral tablets(Clomid 50 mg tablets Global Napi , Egypt)” NCT01212263 ↗ “Clomiphene citrate (Clomid) is often used for assisted reproductive technologies” NCT06701071 ↗ “Clomid is the standard first drug of treatment for ovulation induction” NCT01793038 ↗ “Clomiphene citrate (clomid) (50mg) will be given for 5 days” NCT03178500 ↗ Show 6 more sources
Known as	Clomifene Citrate	“clomifene citrate 50 mg three times daily” NCT04052607 ↗ 5 NCT01389713 ↗ NCT02544776 ↗ NCT03615547 ↗ NCT00478504 ↗ NCT01791751 ↗
Known as	clomiphen citrate	“Initial clomiphen citrate (CC) doses were 50 mg daily for 5 days starting on cycle day 3.” NCT02269306 ↗
Known as	clomiphene	“100 mg clomiphene Citrate (Clomid , global Napi , Egypt) CC tablets taken from day 3 to day 7 of the cycle” NCT02562664 ↗ 31 “Drug: Clomiphene” NCT01679574 ↗ NCT01155518 ↗ NCT02690870 ↗ NCT02294773 ↗ NCT02377479 ↗ NCT02137265 ↗ NCT01607320 ↗ NCT02274311 ↗ NCT01904734 ↗ NCT03989024 ↗ Show 21 more sources
Known as	Omifin	“CC 50 mg/day (Omifin®) + rFSH 150 IU (Ovaleap®)” NCT04983173 ↗
Known as	Ovumid	“Clomiphene citrate (Ovumid®, Iran Hormones Company) 25 mg/day with co-treatment of Letrozole (Letrofem®, Iran Hormones Company) 2.5 mg/day are given from cycle day 3 onwards.” NCT02732808 ↗
Known as	Tecnovula	“clomiphene citrate 50 mg (Tecnovula®)” NCT05753098 ↗
Action	Activate	“Traditionally, clomiphene citrate, an estrogen receptor agonist, is the most used drug for this type of anovulation.” NCT00427700 ↗
Modality	Other / unclassified	“Clomiphene citrate, a selective estrogen receptor modulator (SERM) oral medication which inhibits estrogen effects (feedback) on the brain” NCT01880086 ↗
Route	Oral	“oral clomiphene citrate daily” NCT00005104 ↗