drugset / Trial / NCT01289756
Influence of Pharmacogenetic Factors, Paroxetine and Clarithromycin on Pharmacokinetics of Clomiphene
RandomizedSingle-groupOpen-labelBasic science
Summary
Aim of the study is the clinical validation of the metabolism and the pharmakokinetic of Clomifen in correlation to CYP2D6 and inhibition of CYP3A4.
Timeline
- Start
- 2009-12
- Primary completion
- 2014-11
- Completion
- 2014-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Clarithromycin | Small molecule | 500 mg | — |
| Subject | Clomiphene | Other / unclassified | 100 mg | Oral |
| Subject | Paroxetine | Small molecule | 40 mg | — |