Assessing the Efficacy of Clomiphene Citrate in Patients With Azoospermia and Hypoandrogenism

Withdrawn University of Illinois at Chicago

RandomizedParallel-groupDouble-blindTreatment

Summary

Hypothesis: Prescribed clomiphene citrate to azoospermic patients with hypoandrogenism could improve the sperm retrieval in either fresh sperm or after surgical sperm extraction.

Timeline

Start: 2015-09
Primary completion: 2020-10
Completion: 2020-10

Outcome

Outcome not reported

Stopped (Business): “No funding obtained”

Publications

Results Hussein A, Ozgok Y, Ross L, Niederberger C. Clomiphene administration for cases of nonobstructive azoospermia: a multicenter study. J Androl. 2005 Nov-Dec;26(6):787-91; discussion 792-3. doi: 10.2164/jandrol.04180.
Results Hussein A, Ozgok Y, Ross L, Rao P, Niederberger C. Optimization of spermatogenesis-regulating hormones in patients with non-obstructive azoospermia and its impact on sperm retrieval: a multicentre study. BJU Int. 2013 Mar;111(3 Pt B):E110-4. doi: 10.1111/j.1464-410X.2012.11485.x. Epub 2012 Sep 7.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Clomiphene Citrate	Other / unclassified	50 mg	Oral