drugset / Trial / NCT02380755
Clomiphene Citrate for the Treatment of Obesity Related Male Hypogonadism
Phase 2
Completed
78 enrolled
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo · collab
RandomizedParallel-groupTriple-blindTreatment
Summary
Hypogonadism is a clinical condition that can be associated with obesity in man. Controversy exists regarding if its a condition that needs to be treated. The standard Testosterone Therapy is associated with increase in cardiovascular risks, according to some studies, and leads to infertility. The use of Clomiphene Citrate in this sub population of obese man as an alternative treatment option is not well studied. The aim of this protocol is to evaluate the cardiovascular risks, metabolic and hormonal parameters in a double blinded randomized placebo trial.
Timeline
- Start
- 2015-04
- Primary completion
- 2017-01
- Completion
- 2017-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Clomiphene | Other / unclassified | 50 mg | Oral |