drugset / Trial / NCT03806036

The Effect Of Vitamin D Replacement Therapy On Serum Leptin And Follicular Growth Pattern In Women With Resistant Polycystic Ovary

NCT03806036

Phase 4 Unknown 100 enrolled Cairo University
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The study included 100 female diagnosed with polycystic ovary syndrome. They were classified into 2 groups: Study group included 50 women will receive 300.000 I.U single dose of Vitamin D intramuscular injection (Memphis company) , and in the next menstrual cycle induction done by clomiphen citrate 100mg daily for 5 days starting from third day of menstruation and HMG single dose on 8th day . Control group included 50 women will receive only clomiphen citrate 100mg daily for 5 days starting from third day of menstruation and HMG single dose on 8th day. Serum 25 hydroxy Vitamin D3, Serum Leptin and FSH will be done to all women before and after intervention.

Timeline

Start
2018-01-02
Primary completion
2019-02
Completion
2019-02

Drugs

EvaluationDrugModalityDoseRoute
Comparator Vitamin D Other / unclassified 300000 iu Intramuscular
Comparator Clomiphene Other / unclassified 100 mg