drugset / Trial / NCT03989024

Pulsatile Gonadotropin-releasing Hormone for Infertility in Non-obese Patients With Polycystic Ovary Syndrome

NCT03989024

Phase 4 Unknown 78 enrolled RenJi Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

Polycystic ovary syndrome (PCOS) patients are often accompanied by infertility. Non-obese PCOS infertility is more difficult to treat than obese PCOS. The study included non-obese PCOS patients who had not recovered from regular menstruation after six months of metformin treatment. Half of the patients were treated with clomiphene for ovulation induction and half with GnRH pulse therapy.

Timeline

Start
2019-07-01
Primary completion
2020-12-30
Completion
2021-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Clomiphene Other / unclassified 50 mg
Subject Gonadorelin Protein / enzyme biologic 10 ug