drugset / Trial / NCT03989024
Pulsatile Gonadotropin-releasing Hormone for Infertility in Non-obese Patients With Polycystic Ovary Syndrome
RandomizedParallel-groupOpen-labelTreatment
Summary
Polycystic ovary syndrome (PCOS) patients are often accompanied by infertility. Non-obese PCOS infertility is more difficult to treat than obese PCOS. The study included non-obese PCOS patients who had not recovered from regular menstruation after six months of metformin treatment. Half of the patients were treated with clomiphene for ovulation induction and half with GnRH pulse therapy.
Timeline
- Start
- 2019-07-01
- Primary completion
- 2020-12-30
- Completion
- 2021-12-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Clomiphene | Other / unclassified | 50 mg | — |
| Subject | Gonadorelin | Protein / enzyme biologic | 10 ug | — |