drugset / Trial / NCT02352597
Phytoestrogens as an Alternative to Estradiol in Ovulation Induction in PCOS
RandomizedParallel-groupTriple-blindTreatment
Summary
Prospective study conducted on 150 women with polycystic ovarian syndrome (PCOS) were randomly divided into 3 groups: group I (50 women) received clomiphene citrate (CC) only 50 mg orally every 8 hours started from cycle day 3 for 5 days, group II (50 women) received 2mg estradiol valerate daily from cycle day 7 - 11 in addition to CC and group III (50 women) received phytoestrogen (20mg of cimifuga racemosa from day 1- 12) in addition to CC.
Timeline
- Start
- 2013-01
- Primary completion
- 2015-01
- Completion
- 2015-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cimifuga Racemosa | Unknown | 20 mg | — |
| Comparator | Clomiphene | Other / unclassified | 50 mg | Oral |
| Comparator | estradiol valerate | Unknown | 2 mg | Oral |