drugset / Trial / NCT02381184

Extended Clomiphene Citrate Regimen in Women With Polycystic Ovary Syndrome

NCT02381184

Phase 2/3 Completed 160 enrolled Benha University
RandomizedParallel-groupOpen-labelTreatment

Summary

One hundred and thirty six anovulatory women with CC-resistant PCOS were scheduled randomly into two equal groups. Group A (n=68); received CC (100 mg/day from cycle day 3 for 10 days) for up to six cycles. Group B (n=68) underwent LOD and followed up for 6 months. The primary outcome was the ovulation rate in each group; secondary outcomes were midcycle endometrial thickness and serum estradiol, midluteal serum progesterone, and the rates of clinical pregnancy and abortion.

Timeline

Start
2014-06
Primary completion
2016-07
Completion
2016-07

Drugs

EvaluationDrugModalityDoseRoute
Comparator Clomiphene Other / unclassified 100 mg

Indications