drugset

drugset / Trial / NCT05231980

Efficacy of Pentoxifylline and Alpha Lipoic Acid in PCOS Resistant to Clomiphene Citrate

NCT05231980 ↗

Phase 2 Completed 120 enrolled Ain Shams University Misr University for Science and Technology · collab

RandomizedParallel-groupOpen-labelTreatment

Summary

This study evaluate the addition of PTX and ALA to clomiphene citrate in the treatment of polycystic ovary.

Timeline

Start: 2022-06-05
Primary completion: 2023-05-06
Completion: 2023-06-07

Publications

Morsy AA, Sabri NA, Mourad AM, Mojahed EM, Fahmy SF. New insights into pentoxifylline and alpha-lipoic acid: Co-administration with clomiphene citrate for ovulation induction in anovulatory women with polycystic ovary syndrome. Clin Exp Reprod Med. 2026 Mar;53(1):19-30. doi: 10.5653/cerm.2024.07346. Epub 2025 May 20.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Pentoxifylline	Small molecule	400 mg	—
Background	Clomiphene	Other / unclassified	150 mg	—

Indications