drugset
drugset / Trial / NCT00611897

N-acetylcysteine and NMDA Antagonist Interactions

NCT00611897 ↗

Phase 1/2 Completed 16 enrolled Yale University
RandomizedCrossoverTriple-blind

Summary

This study tests the hypothesis that extrasynaptic mechanisms are critically linked with cognitive effects of NMDA antagonism as evidenced by event-related potentials (ERPs) in healthy humans.

Timeline

Start
2006-01
Primary completion
2011-02
Completion
2011-02

Drugs

EvaluationDrugModalityDoseRoute
Comparator N-acetylcysteine Small molecule 1000 mg Oral
Comparator Ketamine Small molecule 0.29 mg/kg Intravenous

Indications

cognitive disorder