drugset / Trial / NCT00613561

Early Diagnosis and Stem Cell Transplantation for Severe Immunodeficiency Diseases

NCT00613561

Non-randomizedSingle-groupOpen-labelTreatment

Summary

The hypothesis of this study is that children with severe primary immunodeficiencies will benefit from early stem cell transplantation utilizing a reduced intensity conditioning regimen. This regimen is associated with a low risk of complications and will lead to correction of the underlying immunological defects.

Timeline

Start
2007-12
Primary completion
2012-12
Completion
2017-12

Drugs

EvaluationDrugModalityDoseRoute
Subject ANTILYMPHOCYTE IMMUNOGLOBULIN (HORSE) Protein / enzyme biologic
Subject Busulfan Small molecule
Subject Fludarabine Small molecule