Strategies to Reduce Antipsychotic-Associated Weight Gain in Youth

Phase 2 Completed 9 enrolled University of North Carolina, Chapel Hill Foundation of Hope, North Carolina · collab

RandomizedParallel-groupQuadruple-blindPrevention

Summary

The purpose of this pilot study is to determine whether starting metformin in conjunction with a second-generation antipsychotic (SGA) and providing information about healthy eating and activity will prevent or reduce the amount of weight gain and the metabolic changes in adolescent youth typically seen with second-generation antipsychotic medication.

Timeline

Start: 2007-01
Primary completion: 2012-10
Completion: 2012-10

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Metformin	Small molecule	250 mg	Oral
Subject	Metformin	Small molecule	2000 mg	Oral

Indications

No indication recorded.