drugset / Trial / NCT00617409
To Immunize Patients With Extensive Stage SCLC Combined With Chemo With or Without All Trans Retinoic Acid
RandomizedFactorialOpen-labelTreatment
Summary
The purpose of this research study is to test a tumor (cancer) vaccine given along with chemotherapy to determine if this vaccine will increase the chances of the tumor shrinking and/or the amount of time that people who have this disease will live.
Timeline
- Start
- 2007-10-02
- Primary completion
- 2015-09-21
- Completion
- 2019-01-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ad.p53-DC vaccines | Vaccine | 1e+06 cells | Other |
| Subject | Ad.p53-DC vaccines | Vaccine | 5e+06 cells | Other |
| Subject | Tretinoin | Small molecule | 150 mg/m2 | — |
| Background | Paclitaxel | Small molecule | 200 mg/m2 | — |