drugset / Trial / NCT00619307
Transition to Rebif New Formulation
RandomizedParallel-groupOpen-labelSupportive care
Summary
To assess patient satisfaction with respect to the incidence of flu-like symptoms (FLS) in patients with multiple sclerosis transitioned from current Rebif (subcutaneously injected interferon beta-1a, 44 mcg three-times-weekly) to the new formulation of Rebif (RNF) while receiving ibuprofen either prophylactically or only when necessary (PRN) after the occurence of flu-like symptoms.
Timeline
- Start
- 2007-07
- Primary completion
- 2008-04
- Completion
- 2008-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ibuprofen | Small molecule | 400 mg | — |
| Comparator | Interferon beta-1a | Protein / enzyme biologic | 44 ug | Subcutaneous |