Investigating the Acute Effects of THC on Functional Brain Systems

Phase 1 Completed 12 enrolled UMC Utrecht Center for Human Drug Research · collab Leiden University Medical Center · collab TI Pharma · collab

RandomizedCrossoverQuadruple-blindBasic science

Summary

The purpose of this study is to determine whether THC, the main psychoactive ingredient in cannabis, affects functional brain systems underlying memory and reward.

Timeline

Start: 2008-04
Primary completion: 2008-09
Completion: 2008-09

Publications

Bossong MG, Jager G, van Hell HH, Zuurman L, Jansma JM, Mehta MA, van Gerven JM, Kahn RS, Ramsey NF. Effects of Delta9-tetrahydrocannabinol administration on human encoding and recall memory function: a pharmacological FMRI study. J Cogn Neurosci. 2012 Mar;24(3):588-99. doi: 10.1162/jocn_a_00156. Epub 2011 Nov 8.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	delta-9-tetrahydrocannabinol	Other / unclassified	6 mg	Inhaled

Indications

No indication recorded.