drugset / Trial / NCT00631072

In Vitro Expanded Autologous Invariant Natural Killer Cells in Cancer

NCT00631072

NaSingle-groupOpen-labelTreatment

Summary

The purpose of this research study is to determine whether we can purify and grow a population of cells from the participants blood (iNKT cells) and then safely give them back to the participant in increased numbers, and whether these cells will then stimulate the bodies own immune response against the cancer. These iNKT cells have been used in laboratory studies and information from these and other research studies suggest that increasing the number of these cells in the blood can stimulate the immune response against tumors.

Timeline

Start
2008-02
Primary completion
2014-08
Completion
2015-04

Drugs

EvaluationDrugModalityDoseRoute
Subject INKT Cell therapy Intravenous
Subject sargramostim Protein / enzyme biologic Subcutaneous

Indications