The Efficacy of Three Months-prednisolone Therapy for Chronic Eosinophilic Pneumonia

Phase 4 Completed 50 enrolled Hamamatsu University

RandomizedParallel-groupOpen-labelTreatment

Summary

A comparison of 3 months-prednisolone administration with 6 months-prednisolone therapy in the treatment of chronic eosinophilic pneumonia. Three months-prednisolone administration may be as effective as 6 months-therapy.

Timeline

Start: 2008-06
Primary completion: 2010-03
Completion: 2010-03

Outcome

Missed primary endpoint

paper No significant difference was found in the cumulative rate of relapse (p=0.56). PMID 25614171 ↗

Publications

Oyama Y, Fujisawa T, Hashimoto D, Enomoto N, Nakamura Y, Inui N, Kuroishi S, Yokomura K, Toyoshima M, Yamada T, Shirai T, Masuda M, Yasuda K, Hayakawa H, Chida K, Suda T. Efficacy of short-term prednisolone treatment in patients with chronic eosinophilic pneumonia. Eur Respir J. 2015 Jun;45(6):1624-31. doi: 10.1183/09031936.00199614. Epub 2015 Jan 22.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Prednisolone	Other / unclassified	0.5 mg/kg	Oral