drugset / Trial / NCT00635141
The Effect of Hypertonic Saline on the Lung Clearance Index in Patients With Cystic Fibrosis
Phase 3
Completed
20 enrolled
The Hospital for Sick Children
Canadian Cystic Fibrosis Foundation · collab
RandomizedCrossoverTriple-blindTreatment
Summary
This study is examining the effect of hypertonic saline compared to placebo on the Lung Clearance Index in Cystic Fibrosis patients.
Timeline
- Start
- 2008-03
- Primary completion
- 2008-12
- Completion
- 2008-12
Publications
- Results Amin R, Subbarao P, Jabar A, Balkovec S, Jensen R, Kerrigan S, Gustafsson P, Ratjen F. Hypertonic saline improves the LCI in paediatric patients with CF with normal lung function. Thorax. 2010 May;65(5):379-83. doi: 10.1136/thx.2009.125831.
- Wark P, McDonald VM, Smith S. Nebulised hypertonic saline for cystic fibrosis. Cochrane Database Syst Rev. 2023 Jun 14;6(6):CD001506. doi: 10.1002/14651858.CD001506.pub5.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Hypertonic saline | Unknown | 7 % | Inhaled |