drugset / Trial / NCT00637624

N-AcetylCysteine vs. Placebo to Prevent Neurotoxicity Induced by Platinum Containing Chemotherapy

NCT00637624

Terminated 69 enrolled Rijnstate Hospital
RandomizedParallel-groupQuadruple-blindPrevention

Summary

In this study we want to investigate the efficacy of N-acetylcysteine (NAC), which is an anti-oxidant, in the prevention of cisplatin-induced neural toxicity, in patients treated for lung cancer with chemotherapy containing cisplatin.

Timeline

Start
2008-03
Primary completion
2017-07
Completion
2017-07

Drugs

EvaluationDrugModalityDoseRoute
Comparator N-acetylcysteine Small molecule 40 mg/kg Intravenous