drugset / Trial / NCT00637871

Casodex - Nolvadex Combination

NCT00637871

Phase 2 Completed AstraZeneca
RandomizedParallel-groupDouble-blindTreatment

Summary

This study looks at the relationship in the dose of nolvadex and the incidence of gynaecomastia and also Prostate Specific Antigen (PSA) inhibition when co-administered with Casodex. The aim of the study is to assess the optimal dose of nolvadex which will reduce the breast tissue adverse effects without reducing the efficacy of Casodex.

Timeline

Start
2002-11
Primary completion
2005-06
Completion
2005-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Bicalutamide Other / unclassified 150 mg Oral
Comparator Tamoxifen Small molecule Oral