Tocolytics Trial: Intravenous (IV) Magnesium Versus Oral Nifedpine in Fetal Fibronectin (FFN) Postive Population

Phase 3 Terminated 200 enrolled MemorialCare

RandomizedParallel-groupOpen-labelTreatment

Summary

In women with singleton gestations, to contemporarily assess the efficacy of oral nifedipine versus intravenous magnesium sulfate in the acute management of preterm labor in terms of defined early and late neonatal measures

Timeline

Start: 2008-03
Primary completion: 2012-03
Completion: 2012-03

Publications

Wilson A, Hodgetts-Morton VA, Marson EJ, Markland AD, Larkai E, Papadopoulou A, Coomarasamy A, Tobias A, Chou D, Oladapo OT, Price MJ, Morris K, Gallos ID. Tocolytics for delaying preterm birth: a network meta-analysis (0924). Cochrane Database Syst Rev. 2022 Aug 10;8(8):CD014978. doi: 10.1002/14651858.CD014978.pub2.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Magnesium Sulfate	Other / unclassified	3 g	Intravenous
Subject	Nifedlipine	Unknown	20 mg	Oral

Indications

No indication recorded.