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drugset / Trial / NCT00644839

Study Examing The Effect Of Omeprazole On Safety, Tolerability And How The Body Processes An Experimental Drug

NCT00644839 ↗

Phase 1 Completed 28 enrolled Pfizer
Non-randomizedSingle-groupOpen-labelTreatment

Summary

Experiment in the test tube indicated that CP-945,598 becomes less soluble with increase of pH (less acidity). Changes in stomach acid levels may affect the solubility of CP-945,598, therefore, alters its availability in the blood. Omeprazole decreases acid levels in stomach. This study will compare the time course of drug concentrations in the body, safety, and tolerability of CP-945,598 given with and without omeprazole.

Timeline

Start
2008-04
Primary completion
2008-07
Completion
2008-07

Drugs

EvaluationDrugModalityDoseRoute
Subject OTENABANT Small molecule — —

Indications

obesity disorder