drugset / Trial / NCT00667420

Perioperative Panitumumab and Epirubicin, Oxaliplatin and Xeloda (EOX) in Patients With Gastroesophageal Adenocarcinoma

NCT00667420

Phase 1/2 Terminated 17 enrolled Massachusetts General Hospital
NaSingle-groupOpen-labelTreatment

Summary

A pilot study to determine the safety of using perioperative panitumumab with EOX (epirubicin, oxaliplatin, and capecitabine) in patients with adenocarcinoma of the esophagus and stomach.

Timeline

Start
2008-04
Primary completion
2011-06
Completion
2014-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Panitumumab Monoclonal antibody 9 mg/kg Intravenous
Background Capecitabine Small molecule 400 mg/m2
Background Epirubicin Small molecule 50 mg/m2 Intravenous
Background Oxaliplatin Small molecule 100 mg/m2 Intravenous