drugset / Trial / NCT00672646

Study to Investigate the Analgesic Efficacy of a Single Dose of AZD1386

NCT00672646

Phase 2 Completed 103 enrolled AstraZeneca
RandomizedParallel-groupTriple-blindTreatment

Summary

The primary aim of this study is to investigate if AZD1386 can relieve the pain induced by the surgical removal of one lower wisdom-tooth. This will be done by comparing the effect of AZD1386 to placebo ("inactive substance") on pain. A number of patients will instead receive the common painkiller naproxen for comparison purposes. Rescue medication, acetaminophen, will be allowed if a need for additional painkillers would arise. A number of patients will receive naproxen as control.

Timeline

Start
2008-04
Primary completion
2008-06
Completion
2008-06

Drugs

EvaluationDrugModalityDoseRoute
Subject AZD1386 Small molecule 95 mg Oral
Comparator Naproxen Small molecule 500 mg

Indications

No indication recorded.