drugset / Trial / NCT00675272
Organ Donation and Hydrocortisone Treatment
RandomizedParallel-groupTriple-blindPrevention
Summary
Brain death patients who are selected for organ donation very often suffer from haemodynamic instability. To treat this, high amounts of vasoactive drugs(norepinephrine) may be needed to raise blood pressure. However,norepinephrine may have negative influence on several organs causing reduced blood flow ischemia. Our hypothesis is that hydrocortisone treatment may reduce the amount of vasoactive drugs needed to keep the blood pressure stable in patients selected for organ donation.
Timeline
- Start
- 2008-05
- Primary completion
- 2011-08
- Completion
- 2011-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Hydrocortisone | Other / unclassified | 50 mg | Intravenous |
Indications
No indication recorded.