Effect of Intraarticular Steroids on Bone Turnover in Osteoarthritis

Summary

Oral and nasal steroids may enhance osteoporosis by suppressing bone formation. Intra-articular steroids may also suppress bone formation, however, the duration or relationship to a steroid dose has not been established. It is hypothesized that intra-articular steroids suppress bone formation transiently, returning to pretreatment levels within four weeks in subjects with osteoarthritis.

Timeline

Start

2008-05

Primary completion

2009-11

Completion

2010-05

Drugs

Indications