drugset / Trial / NCT00682448
Metformin for the Prevention of the Metabolic Side-effects of Zyprexa
RandomizedParallel-groupQuadruple-blindPrevention
Summary
We hypothesize that metformin co-administered with olanzapine will be well tolerated and associated with significantly less insulin resistance, weight gain and dyslipidemia as compared to olanzapine plus placebo.
Timeline
- Start
- 2007-08
- Primary completion
- 2011-08
- Completion
- 2011-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Metformin | Small molecule | 2000 mg | Oral |