drugset / Trial / NCT00686504
Positron Emission Tomography (PET) Study With [11C]AZ12713580 to Determine Central mGluR5 Receptor Occupancy of AZD2066
Non-randomizedSingle-groupOpen-labelBasic science
Summary
The study is carried out in order to determine the relationship between AZD2066 exposure and mGluR5 receptor occupancy in the brain and to demonstrate that AZD2066 can displace \[11C\]AZ12713580 from mGluR5 binding-sites in the Central Nervous System
Timeline
- Start
- 2008-04
- Primary completion
- 2008-06
- Completion
- 2008-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | AZ12713580 | Unknown | — | Intravenous |
| Subject | AZD2066 | Small molecule | — | Oral |
Indications
No indication recorded.