drugset / Trial / NCT00686855
Topical Dexamethasone and Tacrolimus for the Treatment of Oral Chronic Graft-Versus-Host Disease
Phase 2
Completed
46 enrolled
Brigham and Women's Hospital
Beth Israel Deaconess Medical Center · collabBoston Children's Hospital · collabDana-Farber Cancer Institute · collabMassachusetts General Hospital · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this research study is to determine the effectiveness of topical steroid therapy (with a drug called dexamethasone) and topical tacrolimus therapy for the treatment of oral chronic Graft-Versus-Host Disease (cGVHD)
Timeline
- Start
- 2008-08
- Primary completion
- 2012-12
- Completion
- 2013-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexamethasone | Small molecule | — | Oral |
| Subject | Tacrolimus | Small molecule | — | Oral |