drugset / Trial / NCT00687973
Effect of the Fixed Dose Combination Amlodipine/Valsartan on Central Aortic Blood Pressure in Uncontrolled Essential Hypertension With Amlodipine 5 mg
RandomizedParallel-groupOpen-labelTreatment
Summary
Assess that for an equivalent brachial blood pressure (BP)lowering, a fixed dose combination amlodipine/valsartan based regimen reduces central aortic BP pressure to a larger extent than an atenolol/amlodipine combination based regimen.
Timeline
- Start
- 2008-01
- Primary completion
- 2009-01
- Completion
- 2009-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Amlodipine | Other / unclassified | 10 mg | Oral |
| Comparator | Atenolol | Other / unclassified | 100 mg | Oral |
| Subject | Valsartan | Small molecule | 160 mg | Oral |