drugset / Trial / NCT00688987
The Hypothalamic-Pituitary-Adrenal (HPA) Axis as an Effector System in Weight Regulation
RandomizedParallel-groupSingle-blindTreatment
Summary
Replacing glucocorticoid in a dose dependent manner (including doses within the physiological range) to subjects with adrenal insufficiency will increase visceral fat accumulation independently of total fat mass.
Timeline
- Start
- 2000-08
- Primary completion
- 2004-07
- Completion
- 2004-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Hydrocortisone | Other / unclassified | 15 mg | — |
| Comparator | Hydrocortisone | Other / unclassified | 25 mg | — |
| Comparator | Hydrocortisone | Other / unclassified | 40 mg | — |