drugset / Trial / NCT00689078
Evaluation of the Efficacy of Topical Ophthalmic Steroids in a Modified Conjunctival Allergen Challenge (CAC) Model
RandomizedParallel-groupDouble-blindTreatment
Summary
To evaluate the efficacy of prednisolone acetate 1% ophthalmic suspension as compared to prednisolone acetate 0.12% ophthalmic suspension, loteprednol etabonate 0.2% ophthalmic suspension, and placebo (Tears Naturale® II) in the prevention of the signs and symptoms of allergic conjunctivitis. Comparisons will be made following 1 week of twice daily (BID) dosing and 1 week of four times daily (QID) dosing.
Timeline
- Start
- 2008-05
- Primary completion
- 2008-06
- Completion
- 2008-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Loteprednol Etabonate | Other / unclassified | 0.2 % | Other |
| Comparator | Prednisolone | Other / unclassified | 0.12 % | Other |
| Comparator | Prednisolone | Other / unclassified | 1 % | Other |