drugset / Trial / NCT00689208

Pharmacological Intervention in Insulin Resistance Targeting Autonomic Nerve Activity

NCT00689208

Phase 0 Completed 12 enrolled AstraZeneca
RandomizedCrossoverSingle-blindBasic science

Summary

The present study on pharmacological intervention in autonomic nervous dysregulation(parasympathetic dysfunction,) regarding insulin resistance, is a concept testing in humans tohelp identify potential new pharmacological target sites in the central nervous system.

Timeline

Start
2007-05
Primary completion
2008-10
Completion
2008-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Atropine Other / unclassified 4 ug/kg
Subject Physostigmine Small molecule 0.12 ug/kg

Indications

No indication recorded.