drugset / Trial / NCT00692510
Drug Interaction Study Between AZD3480 and Cytochrome P450
RandomizedCrossoverDouble-blindBasic science
Summary
The purpose of the study is to evaluate if AZD3480 inhibits Cytochrome P450 1A2, 2C19, 3A4, 2C8, 2B6 and UGT1A1 activity.
Timeline
- Start
- 2007-11
- Primary completion
- 2008-09
- Completion
- 2008-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | ispronicline | Small molecule | — | Oral |
| Background | Bilirubin | Small molecule | — | — |
| Background | Bupropion | Small molecule | — | — |
| Background | Caffeine | Small molecule | — | — |
| Background | Midazolam | Small molecule | — | — |
| Background | Omeprazole | Other / unclassified | — | — |
| Background | Rosiglitazone | Small molecule | — | — |