drugset / Trial / NCT00692939
Autologous Stem Cell Transplantation for Crohn's Disease
NaSingle-groupOpen-labelTreatment
Summary
The objective of this study is to evaluate the safety and effectiveness of administering high-dose chemotherapy followed by infusion of autologous CD34-selected peripheral blood stem cells (PBSC) in pediatric and adult patients with severe Crohn's disease.
Timeline
- Start
- 2012-06-26
- Primary completion
- 2026-12
- Completion
- 2027-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | autologous CD34-selected peripheral blood stem cells transplant | Cell therapy | — | — |
| Background | 2-MERCAPTOETHANESULFONIC ACID | Small molecule | — | — |
| Background | ATG | Unknown | — | — |
| Background | Alemtuzumab | Monoclonal antibody | — | — |
| Background | Cyclophosphamide | Other / unclassified | — | — |
| Background | G-CSF | Unknown | — | — |
| Background | Melphalan | Small molecule | — | — |
| Background | Rituximab | Monoclonal antibody | — | — |
| Background | Thiotepa | Other / unclassified | — | — |