drugset / Trial / NCT00693433
Temsirolimus and Dexamethasone in Treating Patients With Recurrent or Refractory Multiple Myeloma
NaSingle-groupOpen-labelTreatment
Summary
This phase I trial is studying the side effects and best dose of temsirolimus when given together with dexamethasone in treating patients with recurrent or refractory multiple myeloma. Temsirolimus may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving temsirolimus together with dexamethasone may kill more cancer cells.
Timeline
- Start
- 2008-12
- Primary completion
- 2010-08
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Temsirolimus | Small molecule | — | Intravenous |
| Background | Dexamethasone | Small molecule | — | Oral |