drugset / Trial / NCT00693433

Temsirolimus and Dexamethasone in Treating Patients With Recurrent or Refractory Multiple Myeloma

NCT00693433

Phase 1 Completed 15 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This phase I trial is studying the side effects and best dose of temsirolimus when given together with dexamethasone in treating patients with recurrent or refractory multiple myeloma. Temsirolimus may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving temsirolimus together with dexamethasone may kill more cancer cells.

Timeline

Start
2008-12
Primary completion
2010-08
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Temsirolimus Small molecule Intravenous
Background Dexamethasone Small molecule Oral

Indications