Feasibility Study of a Vaginal Ring for Delivery of TMC120 (Dapivirine)

Summary

The purpose of this trial was to evaluate the safety and feasibility of using a vaginal ring to deliver the candidate microbicide TMC120 (dapivirine). Twelve women initially underwent 7-day exposure to a placebo ring containing no investigational agent. They then underwent 7-day exposure to a ring containing 120 mg of TMC120 (dapivirine). Feasibility was assessed in terms of safety and tolerability as well as drug delivery.

Timeline

Start

2004-10

Primary completion

2005-01

Completion

2005-01

Drugs

Indications