drugset / Trial / NCT00708123
In Situ Caries of Fluoride Toothpastes
RandomizedCrossoverDouble-blindTreatment
Summary
This study is to evaluate the effect of fluoride dentifrices on enamel with artificial caries lesions in an in situ model.
Timeline
- Start
- 2007-11
- Primary completion
- 2008-04
- Completion
- 2008-04
Outcome
Met primary endpoint
registry NaF/Carbopol Toothpaste (1400 Ppm F) vs NaMFP/NaF Toothpaste (1450 Ppm F); p = 0.0265; Adjusted mean difference 3.97 (95% CI 0.47 to 7.48) NCT00708123 ↗
registry NaF Toothpaste (1350 Ppm F) vs NaMFP/NaF Toothpaste (1450 Ppm F); p = 0.0017; Adjusted mean difference 5.66 (95% CI 2.15 to 9.18) NCT00708123 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | sodium fluoride | Unknown | 250 ppm | Topical |
| Subject | sodium fluoride | Unknown | 1350 ppm | Topical |
| Subject | sodium fluoride | Unknown | 1400 ppm | Topical |
| Subject | sodium fluoride | Unknown | 1450 ppm | Topical |